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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCKBR All Species: 12.12
Human Site: T283 Identified Species: 24.24
UniProt: P32239 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P32239 NP_795344.1 447 48419 T283 N G R C R P E T G A V G E D S
Chimpanzee Pan troglodytes XP_521813 434 46870 T270 N G R C R P E T G A V G E D S
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 T240 G I I S F S Y T R I W S K L K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P56481 453 49153 T289 N G G C R H V T S L T G E D S
Rat Rattus norvegicus P30553 452 48938 T288 N G G C R P V T S V A G E D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514193 322 36434 G181 N L H P V P S G D G S S K I E
Chicken Gallus gallus Q9DDN6 385 43491 T244 A I I S Y A Y T R I W T K L K
Frog Xenopus laevis P70031 453 51139 G298 P S G D E G D G C Y I Q V T K
Zebra Danio Brachydanio rerio XP_002663361 534 59226 Q381 D G D G C Y I Q V S K R P N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P30974 504 58001 Y330 H L F F I Y A Y H N N Q V A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022844 471 53720 A290 S T H T Q K S A M A K Q R V I
Sea Urchin Strong. purpuratus XP_782630 517 58443 R350 L S K K K K G R K A L M D D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 22.6 N.A. N.A. 88.3 87.8 N.A. 35.3 23.4 53.4 45.3 N.A. 21.6 N.A. 29.5 32.6
Protein Similarity: 100 91.5 41.1 N.A. N.A. 92.2 92 N.A. 47.8 43.4 71 62.9 N.A. 37.7 N.A. 47.9 51.4
P-Site Identity: 100 100 6.6 N.A. N.A. 60 66.6 N.A. 13.3 6.6 0 13.3 N.A. 6.6 N.A. 6.6 20
P-Site Similarity: 100 100 13.3 N.A. N.A. 60 66.6 N.A. 20 13.3 13.3 33.3 N.A. 13.3 N.A. 20 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 9 9 0 34 9 0 0 9 0 % A
% Cys: 0 0 0 34 9 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 9 0 9 9 0 0 9 0 9 0 0 0 9 42 0 % D
% Glu: 0 0 0 0 9 0 17 0 0 0 0 0 34 0 9 % E
% Phe: 0 0 9 9 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 42 25 9 0 9 9 17 17 9 0 34 0 0 0 % G
% His: 9 0 17 0 0 9 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 17 17 0 9 0 9 0 0 17 9 0 0 9 9 % I
% Lys: 0 0 9 9 9 17 0 0 9 0 17 0 25 0 25 % K
% Leu: 9 17 0 0 0 0 0 0 0 9 9 0 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % M
% Asn: 42 0 0 0 0 0 0 0 0 9 9 0 0 9 0 % N
% Pro: 9 0 0 9 0 34 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 9 0 0 9 0 0 0 25 0 0 0 % Q
% Arg: 0 0 17 0 34 0 0 9 17 0 0 9 9 0 0 % R
% Ser: 9 17 0 17 0 9 17 0 17 9 9 17 0 0 59 % S
% Thr: 0 9 0 9 0 0 0 50 0 0 9 9 0 9 0 % T
% Val: 0 0 0 0 9 0 17 0 9 9 17 0 17 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % W
% Tyr: 0 0 0 0 9 17 17 9 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _