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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OTX1
All Species:
22.12
Human Site:
S146
Identified Species:
54.07
UniProt:
P32242
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32242
NP_055377.1
354
37327
S146
S
S
S
A
S
S
S
S
A
N
P
A
A
A
A
Chimpanzee
Pan troglodytes
XP_001162799
354
37249
S146
S
S
S
A
S
S
S
S
A
N
P
A
A
A
A
Rhesus Macaque
Macaca mulatta
XP_001084150
354
37249
S146
S
S
S
A
S
S
S
S
A
N
P
A
A
A
A
Dog
Lupus familis
XP_852530
355
37344
S146
S
S
S
G
S
G
A
S
A
N
P
A
A
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P80205
355
37513
S146
S
S
S
A
S
S
A
S
A
N
P
A
A
A
A
Rat
Rattus norvegicus
Q63410
355
37584
S146
S
S
S
A
S
S
A
S
A
N
P
A
A
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PVM0
290
31534
R89
V
Q
V
W
F
K
N
R
R
A
K
C
R
Q
Q
Zebra Danio
Brachydanio rerio
Q91994
323
35189
E122
T
R
E
S
T
G
S
E
S
S
G
Q
F
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22810
542
55168
N179
T
Q
S
S
G
G
N
N
S
N
K
S
S
Q
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93356
278
30883
Q77
A
R
E
R
V
A
D
Q
I
R
L
Q
E
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
99.4
96.9
N.A.
97.1
96.9
N.A.
N.A.
N.A.
55.6
77.4
N.A.
30.6
N.A.
28.5
N.A.
Protein Similarity:
100
98
99.4
97.4
N.A.
98
97.4
N.A.
N.A.
N.A.
64.4
82.7
N.A.
41.5
N.A.
40.1
N.A.
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
N.A.
N.A.
0
6.6
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
N.A.
6.6
40
N.A.
60
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
50
0
10
30
0
60
10
0
60
60
60
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
20
0
0
0
0
10
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
10
30
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
20
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
20
10
0
70
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
10
% P
% Gln:
0
20
0
0
0
0
0
10
0
0
0
20
0
20
10
% Q
% Arg:
0
20
0
10
0
0
0
10
10
10
0
0
10
0
10
% R
% Ser:
60
60
70
20
60
50
40
60
20
10
0
10
10
10
0
% S
% Thr:
20
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% T
% Val:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _