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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA3
All Species:
16.06
Human Site:
S388
Identified Species:
32.12
UniProt:
P32297
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32297
NP_000734.2
505
57480
S388
N
C
F
S
R
A
E
S
K
G
C
K
E
G
Y
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
G387
K
G
K
L
A
S
H
G
E
P
R
H
L
K
E
Rhesus Macaque
Macaca mulatta
XP_001107366
497
56832
K384
R
A
E
S
K
G
C
K
E
G
Y
P
C
Q
D
Dog
Lupus familis
XP_539232
575
65058
T458
N
C
F
R
R
A
E
T
R
G
C
K
E
G
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4G9
499
57091
S382
N
C
F
S
R
A
D
S
K
S
C
K
E
G
Y
Rat
Rattus norvegicus
P04757
499
56979
S382
N
C
F
S
R
A
D
S
K
S
C
K
E
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
S862
N
C
F
S
G
S
G
S
K
C
C
K
E
G
F
Chicken
Gallus gallus
P09481
496
57009
K383
S
S
E
I
K
C
C
K
D
G
F
V
C
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921314
508
58116
Q382
T
S
V
C
R
G
P
Q
L
L
L
C
P
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
F392
V
R
D
S
I
S
D
F
P
S
E
F
K
D
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
A394
N
R
K
F
D
S
R
A
S
T
F
S
I
G
V
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
E432
E
V
V
H
K
E
G
E
N
P
H
S
N
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.3
96.8
79.4
N.A.
91
91
N.A.
46.5
81.1
N.A.
73.6
N.A.
39.8
N.A.
47.7
47.1
Protein Similarity:
100
74.8
97
83.3
N.A.
93.6
93.6
N.A.
49.2
88.3
N.A.
82.4
N.A.
59.5
N.A.
65.9
64
P-Site Identity:
100
0
13.3
73.3
N.A.
86.6
86.6
N.A.
66.6
6.6
N.A.
6.6
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
13.3
26.6
86.6
N.A.
93.3
93.3
N.A.
80
20
N.A.
6.6
N.A.
26.6
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
34
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
42
0
9
0
9
17
0
0
9
42
9
17
0
9
% C
% Asp:
0
0
9
0
9
0
25
0
9
0
0
0
0
9
17
% D
% Glu:
9
0
17
0
0
9
17
9
17
0
9
0
42
0
17
% E
% Phe:
0
0
42
9
0
0
0
9
0
0
17
9
0
0
9
% F
% Gly:
0
9
0
0
9
17
17
9
0
34
0
0
0
59
0
% G
% His:
0
0
0
9
0
0
9
0
0
0
9
9
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
9
0
17
0
25
0
0
17
34
0
0
42
9
9
0
% K
% Leu:
0
0
0
9
0
0
0
0
9
9
9
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
17
0
9
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
17
0
% Q
% Arg:
9
17
0
9
42
0
9
0
9
0
9
0
0
0
9
% R
% Ser:
9
17
0
50
0
34
0
34
9
25
0
17
0
0
9
% S
% Thr:
9
0
0
0
0
0
0
9
0
9
0
0
0
9
0
% T
% Val:
9
9
17
0
0
0
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _