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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA3
All Species:
17.58
Human Site:
S422
Identified Species:
35.15
UniProt:
P32297
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32297
NP_000734.2
505
57480
S422
F
S
A
N
L
T
R
S
S
S
S
E
S
V
D
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
E421
H
P
L
Q
W
V
V
E
N
S
E
H
S
P
E
Rhesus Macaque
Macaca mulatta
XP_001107366
497
56832
E418
L
T
R
S
S
S
S
E
S
V
D
A
V
L
S
Dog
Lupus familis
XP_539232
575
65058
S492
F
S
A
N
L
P
R
S
S
S
S
E
S
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4G9
499
57091
S416
F
S
A
N
L
T
R
S
S
S
S
E
S
V
D
Rat
Rattus norvegicus
P04757
499
56979
S416
F
S
A
N
L
T
R
S
S
S
S
E
S
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
S896
Y
S
A
N
I
T
Q
S
S
S
S
E
S
V
D
Chicken
Gallus gallus
P09481
496
57009
E417
L
T
R
S
S
S
S
E
S
V
D
P
L
F
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921314
508
58116
E416
H
I
S
N
M
T
S
E
G
A
E
D
G
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
V426
P
R
N
L
T
P
E
V
L
Q
A
L
R
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
P428
E
E
S
S
F
T
L
P
R
D
N
S
P
V
R
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
P466
G
N
P
N
I
D
A
P
S
M
S
K
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.3
96.8
79.4
N.A.
91
91
N.A.
46.5
81.1
N.A.
73.6
N.A.
39.8
N.A.
47.7
47.1
Protein Similarity:
100
74.8
97
83.3
N.A.
93.6
93.6
N.A.
49.2
88.3
N.A.
82.4
N.A.
59.5
N.A.
65.9
64
P-Site Identity:
100
13.3
6.6
80
N.A.
100
93.3
N.A.
80
6.6
N.A.
13.3
N.A.
0
N.A.
13.3
20
P-Site Similarity:
100
26.6
33.3
86.6
N.A.
100
100
N.A.
100
26.6
N.A.
40
N.A.
6.6
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
0
0
0
9
0
0
9
9
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
9
17
9
0
0
25
% D
% Glu:
9
9
0
0
0
0
9
34
0
0
17
42
0
0
9
% E
% Phe:
34
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
0
0
0
0
0
0
9
0
0
0
17
17
9
% G
% His:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
9
0
0
17
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
17
0
9
9
34
0
9
0
9
0
0
9
9
9
0
% L
% Met:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
9
59
0
0
0
0
9
0
9
0
0
0
9
% N
% Pro:
9
9
9
0
0
17
0
17
0
0
0
9
9
9
0
% P
% Gln:
0
0
0
9
0
0
9
0
0
9
0
0
0
0
0
% Q
% Arg:
0
9
17
0
0
0
34
0
9
0
0
0
9
0
9
% R
% Ser:
0
42
17
25
17
17
25
42
67
50
50
9
50
0
34
% S
% Thr:
0
17
0
0
9
50
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
9
9
0
17
0
0
9
42
9
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _