KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA3
All Species:
19.39
Human Site:
S447
Identified Species:
38.79
UniProt:
P32297
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32297
NP_000734.2
505
57480
S447
E
I
K
E
A
I
Q
S
V
K
Y
I
A
E
N
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
H446
I
A
E
N
M
K
S
H
N
E
T
K
E
V
E
Rhesus Macaque
Macaca mulatta
XP_001107366
497
56832
I443
A
I
Q
S
V
K
Y
I
A
E
N
M
K
A
Q
Dog
Lupus familis
XP_539232
575
65058
S517
E
I
K
E
A
I
Q
S
V
K
Y
I
A
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4G9
499
57091
S441
E
I
K
E
A
I
Q
S
V
K
Y
I
A
E
N
Rat
Rattus norvegicus
P04757
499
56979
S441
E
I
K
E
A
I
Q
S
V
K
Y
I
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
S921
E
M
K
E
A
I
E
S
V
K
Y
I
A
E
N
Chicken
Gallus gallus
P09481
496
57009
I442
A
I
E
S
V
K
Y
I
A
E
N
M
K
M
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921314
508
58116
S441
F
L
C
M
S
A
V
S
P
Q
V
R
E
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
E451
D
K
D
N
E
I
V
E
D
W
K
F
V
S
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
D453
D
H
L
K
N
E
E
D
D
K
Q
V
I
E
D
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
Q491
D
G
V
K
F
I
A
Q
H
L
K
S
E
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.3
96.8
79.4
N.A.
91
91
N.A.
46.5
81.1
N.A.
73.6
N.A.
39.8
N.A.
47.7
47.1
Protein Similarity:
100
74.8
97
83.3
N.A.
93.6
93.6
N.A.
49.2
88.3
N.A.
82.4
N.A.
59.5
N.A.
65.9
64
P-Site Identity:
100
0
6.6
100
N.A.
100
100
N.A.
86.6
6.6
N.A.
6.6
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
13.3
26.6
100
N.A.
100
100
N.A.
100
26.6
N.A.
26.6
N.A.
13.3
N.A.
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
42
9
9
0
17
0
0
0
42
17
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
0
9
0
0
0
0
9
17
0
0
0
0
9
9
% D
% Glu:
42
0
17
42
9
9
17
9
0
25
0
0
25
50
17
% E
% Phe:
9
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
9
50
0
0
0
59
0
17
0
0
0
42
9
0
9
% I
% Lys:
0
9
42
17
0
25
0
0
0
50
17
9
17
0
0
% K
% Leu:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
9
0
9
9
0
0
0
0
0
0
17
0
9
9
% M
% Asn:
0
0
0
17
9
0
0
0
9
0
17
0
0
0
42
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
34
9
0
9
9
0
0
0
17
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
0
0
17
9
0
9
50
0
0
0
9
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
9
0
17
0
17
0
42
0
9
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
0
0
0
42
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _