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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA3
All Species:
25.76
Human Site:
T334
Identified Species:
51.52
UniProt:
P32297
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32297
NP_000734.2
505
57480
T334
N
V
H
Y
R
T
P
T
T
H
T
M
P
S
W
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
T333
N
I
H
Y
R
T
P
T
T
H
T
M
P
R
W
Rhesus Macaque
Macaca mulatta
XP_001107366
497
56832
M330
R
T
P
T
T
H
T
M
P
S
W
V
K
T
V
Dog
Lupus familis
XP_539232
575
65058
T404
N
V
H
Y
R
T
P
T
T
H
T
M
P
T
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4G9
499
57091
T328
N
V
H
Y
R
T
P
T
T
H
T
M
P
T
W
Rat
Rattus norvegicus
P04757
499
56979
T328
N
V
H
Y
R
T
P
T
T
H
T
M
P
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
K808
N
V
H
Y
R
T
P
K
T
H
T
M
P
Q
W
Chicken
Gallus gallus
P09481
496
57009
M329
R
T
P
K
T
H
T
M
P
V
W
V
R
T
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921314
508
58116
K328
N
V
H
Y
R
T
P
K
T
H
T
M
P
C
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
S338
N
I
H
F
R
S
P
S
T
H
N
M
S
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
T340
V
T
L
S
V
V
V
T
V
V
T
L
N
V
H
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
S378
N
I
H
Y
R
A
P
S
T
H
T
M
R
P
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.3
96.8
79.4
N.A.
91
91
N.A.
46.5
81.1
N.A.
73.6
N.A.
39.8
N.A.
47.7
47.1
Protein Similarity:
100
74.8
97
83.3
N.A.
93.6
93.6
N.A.
49.2
88.3
N.A.
82.4
N.A.
59.5
N.A.
65.9
64
P-Site Identity:
100
86.6
0
93.3
N.A.
93.3
93.3
N.A.
86.6
0
N.A.
86.6
N.A.
46.6
N.A.
13.3
66.6
P-Site Similarity:
100
93.3
13.3
100
N.A.
100
100
N.A.
86.6
13.3
N.A.
86.6
N.A.
73.3
N.A.
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
75
0
0
17
0
0
0
75
0
0
0
0
9
% H
% Ile:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
9
0
0
0
17
0
0
0
0
9
0
0
% K
% Leu:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
17
0
0
0
75
0
0
0
% M
% Asn:
75
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% N
% Pro:
0
0
17
0
0
0
75
0
17
0
0
0
59
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
17
0
0
0
75
0
0
0
0
0
0
0
17
9
0
% R
% Ser:
0
0
0
9
0
9
0
17
0
9
0
0
9
9
0
% S
% Thr:
0
25
0
9
17
59
17
50
75
0
75
0
0
42
0
% T
% Val:
9
50
0
0
9
9
9
0
9
17
0
17
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
67
% W
% Tyr:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _