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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA3
All Species:
22.42
Human Site:
T357
Identified Species:
44.85
UniProt:
P32297
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32297
NP_000734.2
505
57480
T357
L
P
R
V
M
F
M
T
R
P
T
S
N
E
G
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
R356
L
P
Q
V
L
L
M
R
W
P
L
D
K
T
R
Rhesus Macaque
Macaca mulatta
XP_001107366
497
56832
S353
M
F
M
T
R
P
T
S
N
E
G
N
A
Q
K
Dog
Lupus familis
XP_539232
575
65058
T427
L
P
R
V
M
F
M
T
R
P
A
G
S
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4G9
499
57091
T351
L
P
R
V
M
F
M
T
R
P
T
S
T
E
E
Rat
Rattus norvegicus
P04757
499
56979
T351
L
P
R
V
M
F
M
T
R
P
T
S
G
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
T831
L
P
K
I
M
F
M
T
R
P
G
S
N
E
W
Chicken
Gallus gallus
P09481
496
57009
S352
M
F
M
T
R
P
T
S
D
E
E
N
N
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921314
508
58116
T351
L
P
R
V
M
F
M
T
R
P
E
K
D
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
R361
M
P
K
L
M
M
M
R
R
T
Q
Y
T
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
L363
M
P
K
W
M
K
R
L
F
V
D
F
L
P
K
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
K401
L
P
P
L
L
Y
M
K
R
P
K
R
Y
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.3
96.8
79.4
N.A.
91
91
N.A.
46.5
81.1
N.A.
73.6
N.A.
39.8
N.A.
47.7
47.1
Protein Similarity:
100
74.8
97
83.3
N.A.
93.6
93.6
N.A.
49.2
88.3
N.A.
82.4
N.A.
59.5
N.A.
65.9
64
P-Site Identity:
100
33.3
0
73.3
N.A.
86.6
93.3
N.A.
73.3
6.6
N.A.
66.6
N.A.
26.6
N.A.
13.3
33.3
P-Site Similarity:
100
46.6
26.6
86.6
N.A.
86.6
93.3
N.A.
86.6
33.3
N.A.
80
N.A.
46.6
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
9
9
9
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
17
17
0
0
34
17
% E
% Phe:
0
17
0
0
0
50
0
0
9
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
17
9
9
0
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
25
0
0
9
0
9
0
0
9
9
9
0
25
% K
% Leu:
67
0
0
17
17
9
0
9
0
0
9
0
9
9
0
% L
% Met:
34
0
17
0
67
9
75
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
17
25
9
0
% N
% Pro:
0
84
9
0
0
17
0
0
0
67
0
0
0
9
9
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
9
0
0
25
0
% Q
% Arg:
0
0
42
0
17
0
9
17
67
0
0
9
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
17
0
0
0
34
9
0
0
% S
% Thr:
0
0
0
17
0
0
17
50
0
9
25
0
17
9
0
% T
% Val:
0
0
0
50
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _