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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA3
All Species:
33.64
Human Site:
Y470
Identified Species:
67.27
UniProt:
P32297
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32297
NP_000734.2
505
57480
Y470
E
I
Q
D
D
W
K
Y
V
A
M
V
I
D
R
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
D464
K
Y
V
A
M
V
V
D
R
V
F
L
W
V
F
Rhesus Macaque
Macaca mulatta
XP_001107366
497
56832
Y462
E
I
Q
D
D
W
K
Y
V
A
M
V
I
D
R
Dog
Lupus familis
XP_539232
575
65058
Y540
E
I
Q
D
D
W
K
Y
V
A
M
V
I
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4G9
499
57091
Y464
E
I
Q
D
D
W
K
Y
V
A
M
V
I
D
R
Rat
Rattus norvegicus
P04757
499
56979
Y464
E
I
Q
D
D
W
K
Y
V
A
M
V
I
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513131
979
112159
Y944
E
I
Q
D
D
W
K
Y
V
A
M
V
I
D
R
Chicken
Gallus gallus
P09481
496
57009
Y461
E
I
Q
D
D
W
K
Y
V
A
M
V
I
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921314
508
58116
Y473
E
V
Q
D
D
W
K
Y
V
A
M
V
I
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
T476
T
L
S
C
V
F
G
T
L
A
I
I
C
Q
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
F472
S
V
V
M
D
R
I
F
L
I
T
F
T
F
A
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
A510
T
E
D
W
K
Y
V
A
M
V
I
D
R
I
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.3
96.8
79.4
N.A.
91
91
N.A.
46.5
81.1
N.A.
73.6
N.A.
39.8
N.A.
47.7
47.1
Protein Similarity:
100
74.8
97
83.3
N.A.
93.6
93.6
N.A.
49.2
88.3
N.A.
82.4
N.A.
59.5
N.A.
65.9
64
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
40
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
0
75
0
0
0
0
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
9
67
75
0
0
9
0
0
0
9
0
67
0
% D
% Glu:
67
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
9
0
0
9
9
0
9
17
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
59
0
0
0
0
9
0
0
9
17
9
67
9
0
% I
% Lys:
9
0
0
0
9
0
67
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
17
0
0
9
0
0
0
% L
% Met:
0
0
0
9
9
0
0
0
9
0
67
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
67
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
9
0
0
9
0
0
0
9
0
67
% R
% Ser:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% S
% Thr:
17
0
0
0
0
0
0
9
0
0
9
0
9
0
0
% T
% Val:
0
17
17
0
9
9
17
0
67
17
0
67
0
9
0
% V
% Trp:
0
0
0
9
0
67
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
9
0
0
0
9
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _