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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYCR1
All Species:
15.45
Human Site:
S294
Identified Species:
30.91
UniProt:
P32322
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32322
NP_008838.2
319
33361
S294
L
D
K
V
K
L
D
S
P
A
G
T
A
L
S
Chimpanzee
Pan troglodytes
XP_511751
313
32714
S288
L
D
K
V
K
L
D
S
P
A
G
T
A
L
S
Rhesus Macaque
Macaca mulatta
XP_001112743
293
30865
E267
A
S
C
I
R
T
R
E
L
Q
S
M
A
D
Q
Dog
Lupus familis
XP_540491
320
33602
S294
L
D
K
V
K
L
E
S
S
P
G
H
S
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q922W5
309
32355
A281
Q
E
T
I
S
P
A
A
I
K
K
T
V
L
D
Rat
Rattus norvegicus
Q6AY23
320
33655
S294
L
D
R
V
K
L
E
S
P
T
V
S
T
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232432
266
27648
S242
L
D
K
V
K
L
E
S
P
S
L
S
V
A
S
Frog
Xenopus laevis
A1L2Q8
274
28856
K250
F
G
L
H
E
L
E
K
G
G
L
R
A
A
V
Zebra Danio
Brachydanio rerio
Q5SPD7
288
29903
G262
I
H
A
L
E
K
G
G
F
R
A
A
A
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510032
279
29147
V255
K
G
V
L
M
D
A
V
E
A
A
T
N
R
S
Sea Urchin
Strong. purpuratus
XP_788839
276
28973
L252
R
G
G
F
R
K
C
L
I
E
A
V
E
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P54904
276
28606
K252
A
G
V
H
E
L
E
K
G
S
F
R
A
T
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.7
88.4
90
N.A.
89
84
N.A.
N.A.
57.6
38.5
38.5
N.A.
N.A.
N.A.
43.5
42.6
Protein Similarity:
100
94
89
95.9
N.A.
93
92.1
N.A.
N.A.
68.3
52.9
54.5
N.A.
N.A.
N.A.
58.6
60.5
P-Site Identity:
100
100
6.6
60
N.A.
13.3
53.3
N.A.
N.A.
60
13.3
6.6
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
100
100
20
80
N.A.
33.3
80
N.A.
N.A.
80
26.6
33.3
N.A.
N.A.
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
0
17
9
0
25
25
9
50
25
25
% A
% Cys:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
0
0
0
9
17
0
0
0
0
0
0
9
9
% D
% Glu:
0
9
0
0
25
0
42
9
9
9
0
0
9
0
0
% E
% Phe:
9
0
0
9
0
0
0
0
9
0
9
0
0
0
0
% F
% Gly:
0
34
9
0
0
0
9
9
17
9
25
0
0
0
9
% G
% His:
0
9
0
17
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
0
17
0
0
0
0
17
0
0
0
0
9
0
% I
% Lys:
9
0
34
0
42
17
0
17
0
9
9
0
0
0
0
% K
% Leu:
42
0
9
17
0
59
0
9
9
0
17
0
0
42
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
34
9
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% Q
% Arg:
9
0
9
0
17
0
9
0
0
9
0
17
0
9
0
% R
% Ser:
0
9
0
0
9
0
0
42
9
17
9
17
9
0
34
% S
% Thr:
0
0
9
0
0
9
0
0
0
9
0
34
9
9
0
% T
% Val:
0
0
17
42
0
0
0
9
0
0
9
9
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _