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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC8A1 All Species: 31.21
Human Site: Y457 Identified Species: 85.83
UniProt: P32418 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P32418 NP_001106271.1 973 108547 Y457 T A N A G S D Y E F T E G T V
Chimpanzee Pan troglodytes XP_001137264 973 108569 Y457 T A N A G S D Y E F T E G T V
Rhesus Macaque Macaca mulatta NP_001028033 934 104313 C419 T Y Q C L E N C G T V A L T I
Dog Lupus familis XP_532945 981 109185 Y454 T A N A G S D Y E F T E G T V
Cat Felis silvestris
Mouse Mus musculus P70414 970 108017 Y454 T A N A A S D Y E F T E G T V
Rat Rattus norvegicus Q01728 971 108166 Y454 T A N A G S D Y E F T E G T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505845 972 107782 Y456 T A N A G S D Y E F T E G T V
Chicken Gallus gallus NP_001072941 969 107752 Y454 T A N A G S D Y E F T E G T V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032179 974 108103 Y460 T A N A G S D Y Q F T E G V I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 93.5 95.6 N.A. 94.4 94.9 N.A. 92.6 90.2 N.A. 76.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.9 94.7 97 N.A. 97.4 97.7 N.A. 95.3 95.4 N.A. 87.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 100 N.A. 93.3 100 N.A. 100 100 N.A. 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 93.3 100 N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 89 0 89 12 0 0 0 0 0 0 12 0 0 0 % A
% Cys: 0 0 0 12 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 89 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 12 0 0 78 0 0 89 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 89 0 0 0 0 0 % F
% Gly: 0 0 0 0 78 0 0 0 12 0 0 0 89 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 12 0 0 0 0 0 0 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 89 0 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 12 0 0 0 0 0 12 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 89 0 0 0 0 0 0 0 0 0 % S
% Thr: 100 0 0 0 0 0 0 0 0 12 89 0 0 89 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 12 0 0 12 78 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 0 89 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _