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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPD
All Species:
24.24
Human Site:
S290
Identified Species:
38.1
UniProt:
P32754
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32754
NP_002141.1
393
44934
S290
E
R
G
L
E
F
L
S
V
P
S
T
Y
Y
K
Chimpanzee
Pan troglodytes
XP_528667
393
44884
S290
E
R
G
L
E
F
L
S
V
P
S
T
Y
Y
K
Rhesus Macaque
Macaca mulatta
XP_001096175
393
44868
S290
E
R
G
M
E
F
L
S
V
P
S
T
Y
Y
K
Dog
Lupus familis
XP_853422
393
44850
A290
D
R
G
M
E
F
L
A
V
P
S
T
Y
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
P49429
393
45036
A290
E
R
G
T
E
F
L
A
A
P
S
S
Y
Y
K
Rat
Rattus norvegicus
P32755
393
45094
A290
E
R
G
M
E
F
L
A
V
P
S
S
Y
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415144
393
44954
D290
Q
R
G
M
Q
F
M
D
V
P
S
S
Y
Y
Q
Frog
Xenopus laevis
NP_001088204
393
44771
S290
E
R
G
M
E
F
M
S
V
P
S
S
Y
Y
Q
Zebra Danio
Brachydanio rerio
Q6TGZ5
397
45192
S291
A
R
G
L
E
F
L
S
A
P
D
N
Y
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730536
380
43278
T289
A
R
G
T
E
F
L
T
I
P
S
S
Y
Y
E
Honey Bee
Apis mellifera
XP_001121254
388
44678
D297
A
R
G
M
E
F
L
D
V
P
D
T
Y
Y
D
Nematode Worm
Caenorhab. elegans
Q22633
393
44365
F289
L
R
A
R
G
C
E
F
L
S
I
P
S
S
Y
Sea Urchin
Strong. purpuratus
XP_798672
558
63023
S465
A
R
G
M
N
F
L
S
I
P
D
T
Y
Y
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93836
445
48797
F332
K
R
S
S
I
G
G
F
D
F
M
P
S
P
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q872T7
412
46010
N319
A
R
G
V
E
F
I
N
V
P
S
T
Y
Y
D
Conservation
Percent
Protein Identity:
100
99.7
97.1
92.1
N.A.
89.8
89.8
N.A.
N.A.
76.5
75
71.7
N.A.
60.5
62.5
60
45.8
Protein Similarity:
100
100
98.9
97.9
N.A.
95.4
96.1
N.A.
N.A.
89
86.7
83.6
N.A.
75.8
78.6
73.5
55.5
P-Site Identity:
100
100
93.3
80
N.A.
73.3
73.3
N.A.
N.A.
53.3
73.3
66.6
N.A.
60
66.6
6.6
60
P-Site Similarity:
100
100
100
100
N.A.
86.6
100
N.A.
N.A.
93.3
100
73.3
N.A.
86.6
73.3
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
N.A.
51.7
Protein Similarity:
N.A.
N.A.
N.A.
44.2
N.A.
68.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
7
0
0
0
0
20
14
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
14
7
0
20
0
0
0
14
% D
% Glu:
40
0
0
0
74
0
7
0
0
0
0
0
0
0
14
% E
% Phe:
0
0
0
0
0
87
0
14
0
7
0
0
0
0
0
% F
% Gly:
0
0
87
0
7
7
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
7
0
14
0
7
0
0
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% K
% Leu:
7
0
0
20
0
0
67
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
47
0
0
14
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
7
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
87
0
14
0
7
7
% P
% Gln:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
14
% Q
% Arg:
0
100
0
7
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
7
7
0
0
0
40
0
7
67
34
14
7
0
% S
% Thr:
0
0
0
14
0
0
0
7
0
0
0
47
0
0
7
% T
% Val:
0
0
0
7
0
0
0
0
60
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
87
87
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _