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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPD
All Species:
18.48
Human Site:
Y105
Identified Species:
29.05
UniProt:
P32754
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32754
NP_002141.1
393
44934
Y105
F
E
V
E
D
C
D
Y
I
V
Q
K
A
R
E
Chimpanzee
Pan troglodytes
XP_528667
393
44884
Y105
F
E
V
E
D
C
D
Y
I
V
Q
K
A
R
E
Rhesus Macaque
Macaca mulatta
XP_001096175
393
44868
Y105
F
E
V
E
D
C
D
Y
I
V
Q
K
A
R
E
Dog
Lupus familis
XP_853422
393
44850
Y105
F
E
V
E
D
C
D
Y
I
V
Q
K
A
R
E
Cat
Felis silvestris
Mouse
Mus musculus
P49429
393
45036
H105
F
E
V
E
D
C
D
H
I
V
Q
K
A
R
E
Rat
Rattus norvegicus
P32755
393
45094
H105
F
E
V
E
D
C
E
H
I
V
Q
K
A
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415144
393
44954
F105
F
E
V
E
D
C
D
F
I
V
Q
K
A
K
E
Frog
Xenopus laevis
NP_001088204
393
44771
F105
F
E
V
E
D
C
E
F
I
V
Q
K
A
R
Q
Zebra Danio
Brachydanio rerio
Q6TGZ5
397
45192
F105
F
L
V
E
D
C
D
F
L
V
K
K
A
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730536
380
43278
A105
F
E
V
E
D
L
N
A
I
F
T
L
A
V
S
Honey Bee
Apis mellifera
XP_001121254
388
44678
I113
F
N
V
E
N
I
D
I
I
V
K
I
A
K
E
Nematode Worm
Caenorhab. elegans
Q22633
393
44365
S104
F
E
V
E
D
L
D
S
I
I
A
H
A
K
A
Sea Urchin
Strong. purpuratus
XP_798672
558
63023
G280
F
E
V
K
D
L
A
G
V
V
E
T
A
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93836
445
48797
S151
I
E
V
E
D
A
E
S
A
F
S
I
S
V
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q872T7
412
46010
G134
F
E
V
D
N
V
D
G
V
F
H
K
A
V
A
Conservation
Percent
Protein Identity:
100
99.7
97.1
92.1
N.A.
89.8
89.8
N.A.
N.A.
76.5
75
71.7
N.A.
60.5
62.5
60
45.8
Protein Similarity:
100
100
98.9
97.9
N.A.
95.4
96.1
N.A.
N.A.
89
86.7
83.6
N.A.
75.8
78.6
73.5
55.5
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
N.A.
86.6
80
66.6
N.A.
46.6
53.3
53.3
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
53.3
73.3
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
N.A.
51.7
Protein Similarity:
N.A.
N.A.
N.A.
44.2
N.A.
68.4
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
7
7
7
0
7
0
94
0
20
% A
% Cys:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
87
0
67
0
0
0
0
0
0
0
0
% D
% Glu:
0
87
0
87
0
0
20
0
0
0
7
0
0
0
60
% E
% Phe:
94
0
0
0
0
0
0
20
0
20
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
14
0
0
7
7
0
0
0
% H
% Ile:
7
0
0
0
0
7
0
7
74
7
0
14
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
14
67
0
27
7
% K
% Leu:
0
7
0
0
0
20
0
0
7
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
14
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% R
% Ser:
0
0
0
0
0
0
0
14
0
0
7
0
7
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% T
% Val:
0
0
100
0
0
7
0
0
14
74
0
0
0
27
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
27
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _