KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H1
All Species:
17.58
Human Site:
S158
Identified Species:
27.62
UniProt:
P32780
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32780
NP_001135779.1
548
62032
S158
A
T
D
S
S
S
T
S
N
H
K
Q
D
V
G
Chimpanzee
Pan troglodytes
XP_001173101
548
62049
S158
A
T
D
S
S
S
T
S
N
H
K
Q
D
V
G
Rhesus Macaque
Macaca mulatta
XP_001085569
560
63083
L170
G
T
R
H
H
S
R
L
I
F
I
F
L
V
Q
Dog
Lupus familis
XP_534083
548
62056
S158
A
T
E
S
S
S
T
S
N
H
K
Q
D
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBA9
547
61833
S157
N
A
T
D
S
S
T
S
S
H
K
Q
D
V
G
Rat
Rattus norvegicus
NP_001101955
516
58033
D130
V
L
F
Q
L
Y
K
D
L
V
V
S
Q
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509381
298
33953
Chicken
Gallus gallus
XP_421013
548
62252
A157
N
A
G
D
N
F
A
A
P
S
K
Q
D
V
G
Frog
Xenopus laevis
NP_001080277
532
59910
D130
V
L
F
Q
L
Y
K
D
L
V
V
S
Q
V
I
Zebra Danio
Brachydanio rerio
NP_001004596
550
62395
S158
S
V
D
H
S
P
S
S
N
N
V
Q
E
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960E8
585
66321
M158
K
D
H
A
L
K
K
M
G
R
S
Q
E
I
G
Honey Bee
Apis mellifera
XP_623390
563
64488
K158
A
E
Y
T
Q
A
K
K
S
Q
R
Q
E
I
G
Nematode Worm
Caenorhab. elegans
NP_499880
532
61378
N143
K
I
L
Q
E
D
R
N
L
E
K
L
Y
Q
N
Sea Urchin
Strong. purpuratus
XP_798784
547
61424
S161
F
A
A
A
S
S
A
S
A
S
A
S
D
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9P5N7
663
73012
W195
A
S
F
N
S
Q
F
W
A
T
R
I
S
L
L
Conservation
Percent
Protein Identity:
100
99.6
84.8
98.1
N.A.
97
91.2
N.A.
51.2
89.4
79.7
76.7
N.A.
43.5
49
30.4
51.2
Protein Similarity:
100
99.8
88.3
98.9
N.A.
98.3
92.8
N.A.
53.2
94.1
88.5
88.5
N.A.
62.5
70.5
51
73.7
P-Site Identity:
100
100
20
93.3
N.A.
66.6
6.6
N.A.
0
33.3
6.6
46.6
N.A.
13.3
20
6.6
33.3
P-Site Similarity:
100
100
20
100
N.A.
73.3
6.6
N.A.
0
46.6
6.6
73.3
N.A.
33.3
60
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
39.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
20
7
14
0
7
14
7
14
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
20
14
0
7
0
14
0
0
0
0
40
0
0
% D
% Glu:
0
7
7
0
7
0
0
0
0
7
0
0
20
0
0
% E
% Phe:
7
0
20
0
0
7
7
0
0
7
0
7
0
0
0
% F
% Gly:
7
0
7
0
0
0
0
0
7
0
0
0
0
7
60
% G
% His:
0
0
7
14
7
0
0
0
0
27
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
7
0
7
7
0
14
14
% I
% Lys:
14
0
0
0
0
7
27
7
0
0
40
0
0
0
0
% K
% Leu:
0
14
7
0
20
0
0
7
20
0
0
7
7
7
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
14
0
0
7
7
0
0
7
27
7
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
20
7
7
0
0
0
7
0
54
14
7
7
% Q
% Arg:
0
0
7
0
0
0
14
0
0
7
14
0
0
0
0
% R
% Ser:
7
7
0
20
47
40
7
40
14
14
7
20
7
0
0
% S
% Thr:
0
27
7
7
0
0
27
0
0
7
0
0
0
0
0
% T
% Val:
14
7
0
0
0
0
0
0
0
14
20
0
0
60
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
14
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _