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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H1
All Species:
23.33
Human Site:
S290
Identified Species:
36.67
UniProt:
P32780
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32780
NP_001135779.1
548
62032
S290
I
S
S
V
P
S
A
S
N
S
K
S
I
K
E
Chimpanzee
Pan troglodytes
XP_001173101
548
62049
S290
I
S
S
V
P
S
A
S
N
S
K
S
I
K
E
Rhesus Macaque
Macaca mulatta
XP_001085569
560
63083
S302
I
S
S
V
P
S
A
S
N
S
K
S
I
K
E
Dog
Lupus familis
XP_534083
548
62056
S290
I
S
S
V
P
S
T
S
N
S
K
S
I
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBA9
547
61833
S289
I
S
S
V
P
S
T
S
N
S
K
S
I
K
E
Rat
Rattus norvegicus
NP_001101955
516
58033
G260
L
K
T
M
V
S
L
G
V
K
N
P
M
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509381
298
33953
Y47
R
F
T
I
S
H
M
Y
A
D
I
K
C
Q
K
Chicken
Gallus gallus
XP_421013
548
62252
S289
V
A
P
V
A
S
T
S
N
A
S
K
S
A
R
Frog
Xenopus laevis
NP_001080277
532
59910
G260
L
K
S
M
V
S
Q
G
V
K
N
P
M
L
D
Zebra Danio
Brachydanio rerio
NP_001004596
550
62395
S290
T
A
A
A
P
P
A
S
N
T
A
N
K
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960E8
585
66321
V290
S
V
A
G
D
R
N
V
V
N
S
G
N
I
V
Honey Bee
Apis mellifera
XP_623390
563
64488
K290
N
G
P
S
K
S
D
K
I
S
G
N
I
V
H
Nematode Worm
Caenorhab. elegans
NP_499880
532
61378
Q276
K
M
T
A
E
K
I
Q
R
K
R
F
D
L
E
Sea Urchin
Strong. purpuratus
XP_798784
547
61424
P291
I
N
E
V
R
C
T
P
S
Y
T
S
N
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9P5N7
663
73012
L336
G
G
F
R
G
G
N
L
K
D
V
E
M
R
P
Conservation
Percent
Protein Identity:
100
99.6
84.8
98.1
N.A.
97
91.2
N.A.
51.2
89.4
79.7
76.7
N.A.
43.5
49
30.4
51.2
Protein Similarity:
100
99.8
88.3
98.9
N.A.
98.3
92.8
N.A.
53.2
94.1
88.5
88.5
N.A.
62.5
70.5
51
73.7
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
0
26.6
13.3
26.6
N.A.
0
20
6.6
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
40
N.A.
26.6
46.6
40
53.3
N.A.
13.3
26.6
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
39.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
14
14
7
0
27
0
7
7
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
0
7
0
7
0
0
14
0
0
7
0
20
% D
% Glu:
0
0
7
0
7
0
0
0
0
0
0
7
0
0
40
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
7
14
0
7
7
7
0
14
0
0
7
7
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% H
% Ile:
40
0
0
7
0
0
7
0
7
0
7
0
40
7
0
% I
% Lys:
7
14
0
0
7
7
0
7
7
20
34
14
7
40
7
% K
% Leu:
14
0
0
0
0
0
7
7
0
0
0
0
0
20
7
% L
% Met:
0
7
0
14
0
0
7
0
0
0
0
0
20
0
0
% M
% Asn:
7
7
0
0
0
0
14
0
47
7
14
14
14
0
0
% N
% Pro:
0
0
14
0
40
7
0
7
0
0
0
14
0
0
7
% P
% Gln:
0
0
0
0
0
0
7
7
0
0
0
0
0
7
0
% Q
% Arg:
7
0
0
7
7
7
0
0
7
0
7
0
0
7
7
% R
% Ser:
7
34
40
7
7
60
0
47
7
40
14
40
7
0
0
% S
% Thr:
7
0
20
0
0
0
27
0
0
7
7
0
0
7
0
% T
% Val:
7
7
0
47
14
0
0
7
20
0
7
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _