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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H1
All Species:
31.21
Human Site:
S391
Identified Species:
49.05
UniProt:
P32780
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32780
NP_001135779.1
548
62032
S391
H
G
P
T
P
I
Q
S
L
Q
Y
A
T
S
Q
Chimpanzee
Pan troglodytes
XP_001173101
548
62049
S391
H
G
P
T
P
I
Q
S
L
Q
Y
A
T
S
Q
Rhesus Macaque
Macaca mulatta
XP_001085569
560
63083
S403
H
G
P
T
P
I
Q
S
L
Q
Y
A
T
S
Q
Dog
Lupus familis
XP_534083
548
62056
S391
H
G
P
T
P
I
Q
S
L
Q
Y
A
T
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBA9
547
61833
S390
H
G
P
T
P
I
Q
S
L
Q
Y
A
T
S
Q
Rat
Rattus norvegicus
NP_001101955
516
58033
Y359
K
L
Q
E
S
I
E
Y
E
D
L
G
N
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509381
298
33953
F142
Q
V
I
S
A
E
E
F
W
A
N
R
L
T
M
Chicken
Gallus gallus
XP_421013
548
62252
S391
H
G
P
T
P
I
Q
S
Q
Q
Y
A
T
S
Q
Frog
Xenopus laevis
NP_001080277
532
59910
Y359
K
L
Q
E
A
I
E
Y
E
D
L
D
Q
T
N
Zebra Danio
Brachydanio rerio
NP_001004596
550
62395
S393
H
G
P
V
P
L
Q
S
Q
H
Y
S
T
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960E8
585
66321
N426
V
Q
N
S
M
Y
D
N
H
N
D
P
M
S
L
Honey Bee
Apis mellifera
XP_623390
563
64488
E404
S
N
I
E
P
T
S
E
E
L
L
I
T
L
N
Nematode Worm
Caenorhab. elegans
NP_499880
532
61378
R375
E
D
E
V
Q
I
V
R
I
S
S
S
A
K
A
Sea Urchin
Strong. purpuratus
XP_798784
547
61424
S389
H
G
P
T
V
V
Q
S
T
D
Y
F
S
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9P5N7
663
73012
N476
P
D
S
D
D
E
G
N
N
S
L
D
S
K
S
Conservation
Percent
Protein Identity:
100
99.6
84.8
98.1
N.A.
97
91.2
N.A.
51.2
89.4
79.7
76.7
N.A.
43.5
49
30.4
51.2
Protein Similarity:
100
99.8
88.3
98.9
N.A.
98.3
92.8
N.A.
53.2
94.1
88.5
88.5
N.A.
62.5
70.5
51
73.7
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
0
93.3
6.6
66.6
N.A.
6.6
13.3
6.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
20
93.3
20
80
N.A.
20
13.3
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
39.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
0
0
0
0
7
0
40
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
7
7
0
7
0
0
20
7
14
0
0
0
% D
% Glu:
7
0
7
20
0
14
20
7
20
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% F
% Gly:
0
54
0
0
0
0
7
0
0
0
0
7
0
0
0
% G
% His:
54
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
0
0
14
0
0
60
0
0
7
0
0
7
0
0
0
% I
% Lys:
14
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% K
% Leu:
0
14
0
0
0
7
0
0
34
7
27
0
7
7
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
7
% M
% Asn:
0
7
7
0
0
0
0
14
7
7
7
0
7
7
20
% N
% Pro:
7
0
54
0
54
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
7
7
14
0
7
0
54
0
14
40
0
0
7
0
47
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% R
% Ser:
7
0
7
14
7
0
7
54
0
14
7
14
14
60
7
% S
% Thr:
0
0
0
47
0
7
0
0
7
0
0
0
54
14
0
% T
% Val:
7
7
0
14
7
7
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
14
0
0
54
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _