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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H1
All Species:
25.76
Human Site:
T270
Identified Species:
40.48
UniProt:
P32780
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32780
NP_001135779.1
548
62032
T270
K
N
P
L
L
D
L
T
A
L
E
D
K
P
L
Chimpanzee
Pan troglodytes
XP_001173101
548
62049
T270
K
N
P
L
L
D
L
T
A
L
E
D
K
P
L
Rhesus Macaque
Macaca mulatta
XP_001085569
560
63083
T282
K
N
P
L
L
D
L
T
A
L
E
D
K
P
L
Dog
Lupus familis
XP_534083
548
62056
T270
K
N
P
L
L
D
L
T
A
L
E
D
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBA9
547
61833
T269
K
N
P
M
L
D
L
T
S
L
E
D
K
P
L
Rat
Rattus norvegicus
NP_001101955
516
58033
D240
R
L
N
T
G
S
K
D
L
F
A
E
C
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509381
298
33953
M27
Q
D
G
A
L
Y
L
M
A
E
R
I
A
W
A
Chicken
Gallus gallus
XP_421013
548
62252
T269
K
N
P
M
I
D
L
T
A
L
E
D
R
T
L
Frog
Xenopus laevis
NP_001080277
532
59910
D240
R
L
N
S
G
A
K
D
L
F
A
E
C
A
K
Zebra Danio
Brachydanio rerio
NP_001004596
550
62395
L270
K
N
P
M
V
D
L
L
A
L
E
D
K
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960E8
585
66321
K270
G
D
P
L
L
D
L
K
K
F
E
D
V
P
L
Honey Bee
Apis mellifera
XP_623390
563
64488
S270
D
D
P
L
V
D
I
S
S
F
E
D
Q
T
L
Nematode Worm
Caenorhab. elegans
NP_499880
532
61378
F256
L
P
N
P
K
D
P
F
A
E
C
V
R
D
D
Sea Urchin
Strong. purpuratus
XP_798784
547
61424
D271
E
A
N
Q
T
V
Q
D
P
L
L
D
I
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9P5N7
663
73012
P316
K
I
T
A
T
S
V
P
P
I
I
N
I
E
G
Conservation
Percent
Protein Identity:
100
99.6
84.8
98.1
N.A.
97
91.2
N.A.
51.2
89.4
79.7
76.7
N.A.
43.5
49
30.4
51.2
Protein Similarity:
100
99.8
88.3
98.9
N.A.
98.3
92.8
N.A.
53.2
94.1
88.5
88.5
N.A.
62.5
70.5
51
73.7
P-Site Identity:
100
100
100
93.3
N.A.
86.6
0
N.A.
20
73.3
0
73.3
N.A.
60
40
13.3
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
13.3
N.A.
33.3
93.3
13.3
86.6
N.A.
66.6
80
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
39.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
14
0
7
0
0
54
0
14
0
7
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
14
0
0
% C
% Asp:
7
20
0
0
0
67
0
20
0
0
0
67
0
7
7
% D
% Glu:
7
0
0
0
0
0
0
0
0
14
60
14
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
27
0
0
0
0
0
% F
% Gly:
7
0
7
0
14
0
0
0
0
0
0
0
0
0
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
7
0
0
7
7
7
14
0
0
% I
% Lys:
54
0
0
0
7
0
14
7
7
0
0
0
40
0
14
% K
% Leu:
7
14
0
40
47
0
60
7
14
54
7
0
0
0
60
% L
% Met:
0
0
0
20
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
47
27
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
7
60
7
0
0
7
7
14
0
0
0
0
34
0
% P
% Gln:
7
0
0
7
0
0
7
0
0
0
0
0
7
7
0
% Q
% Arg:
14
0
0
0
0
0
0
0
0
0
7
0
14
0
0
% R
% Ser:
0
0
0
7
0
14
0
7
14
0
0
0
0
7
0
% S
% Thr:
0
0
7
7
14
0
0
40
0
0
0
0
0
20
0
% T
% Val:
0
0
0
0
14
7
7
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _