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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H1
All Species:
18.18
Human Site:
T415
Identified Species:
28.57
UniProt:
P32780
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32780
NP_001135779.1
548
62032
T415
R
Q
E
M
E
A
Y
T
P
K
L
T
Q
V
L
Chimpanzee
Pan troglodytes
XP_001173101
548
62049
T415
R
Q
E
M
E
A
Y
T
P
K
L
T
Q
V
L
Rhesus Macaque
Macaca mulatta
XP_001085569
560
63083
T427
K
Q
E
M
E
A
Y
T
P
K
L
T
Q
V
L
Dog
Lupus familis
XP_534083
548
62056
T415
R
Q
E
M
E
A
Y
T
P
K
L
T
Q
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBA9
547
61833
T414
R
Q
E
M
E
A
Y
T
P
K
L
T
Q
V
L
Rat
Rattus norvegicus
NP_001101955
516
58033
H383
K
K
S
D
R
Y
Y
H
G
P
T
P
I
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509381
298
33953
I166
N
H
R
Q
D
V
G
I
S
A
A
F
L
A
D
Chicken
Gallus gallus
XP_421013
548
62252
V415
R
Q
E
M
E
A
Y
V
P
N
L
T
Q
V
L
Frog
Xenopus laevis
NP_001080277
532
59910
H383
K
K
S
D
R
Y
Y
H
G
P
T
P
I
Q
S
Zebra Danio
Brachydanio rerio
NP_001004596
550
62395
K417
Q
H
E
M
R
S
Y
K
P
Q
L
T
Q
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960E8
585
66321
R450
N
S
E
S
W
L
N
R
N
V
Q
R
T
F
I
Honey Bee
Apis mellifera
XP_623390
563
64488
R428
L
T
G
N
S
I
P
R
Q
L
A
T
S
L
V
Nematode Worm
Caenorhab. elegans
NP_499880
532
61378
V399
M
T
R
Y
K
A
L
V
T
D
Y
F
Q
N
S
Sea Urchin
Strong. purpuratus
XP_798784
547
61424
V413
Q
S
E
V
M
S
S
V
P
N
L
H
K
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9P5N7
663
73012
Q500
R
A
A
L
R
F
A
Q
N
Q
I
L
E
S
M
Conservation
Percent
Protein Identity:
100
99.6
84.8
98.1
N.A.
97
91.2
N.A.
51.2
89.4
79.7
76.7
N.A.
43.5
49
30.4
51.2
Protein Similarity:
100
99.8
88.3
98.9
N.A.
98.3
92.8
N.A.
53.2
94.1
88.5
88.5
N.A.
62.5
70.5
51
73.7
P-Site Identity:
100
100
93.3
100
N.A.
100
6.6
N.A.
0
86.6
6.6
53.3
N.A.
6.6
6.6
13.3
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
6.6
86.6
20
80
N.A.
13.3
20
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
39.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
47
7
0
0
7
14
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
14
7
0
0
0
0
7
0
0
0
0
7
% D
% Glu:
0
0
60
0
40
0
0
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
14
0
7
0
% F
% Gly:
0
0
7
0
0
0
7
0
14
0
0
0
0
0
0
% G
% His:
0
14
0
0
0
0
0
14
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
7
0
0
7
0
14
0
14
% I
% Lys:
20
14
0
0
7
0
0
7
0
34
0
0
7
0
0
% K
% Leu:
7
0
0
7
0
7
7
0
0
7
54
7
7
7
40
% L
% Met:
7
0
0
47
7
0
0
0
0
0
0
0
0
0
14
% M
% Asn:
14
0
0
7
0
0
7
0
14
14
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
7
0
54
14
0
14
0
0
0
% P
% Gln:
14
40
0
7
0
0
0
7
7
14
7
0
54
14
0
% Q
% Arg:
40
0
14
0
27
0
0
14
0
0
0
7
0
0
0
% R
% Ser:
0
14
14
7
7
14
7
0
7
0
0
0
7
7
20
% S
% Thr:
0
14
0
0
0
0
0
34
7
0
14
54
7
0
0
% T
% Val:
0
0
0
7
0
7
0
20
0
7
0
0
0
54
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
14
60
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _