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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H1
All Species:
25.76
Human Site:
Y207
Identified Species:
40.48
UniProt:
P32780
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32780
NP_001135779.1
548
62032
Y207
Y
P
A
V
K
M
K
Y
A
E
N
V
P
H
N
Chimpanzee
Pan troglodytes
XP_001173101
548
62049
Y207
Y
P
A
V
K
M
K
Y
A
E
N
V
P
H
N
Rhesus Macaque
Macaca mulatta
XP_001085569
560
63083
Y219
S
P
T
V
K
M
K
Y
A
E
N
V
P
H
N
Dog
Lupus familis
XP_534083
548
62056
Y207
Y
P
A
V
K
M
K
Y
A
E
N
V
P
H
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBA9
547
61833
Y206
Y
P
A
V
K
M
K
Y
A
E
T
V
P
H
N
Rat
Rattus norvegicus
NP_001101955
516
58033
G179
D
V
R
P
Q
T
D
G
C
N
G
L
R
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509381
298
33953
Chicken
Gallus gallus
XP_421013
548
62252
Y206
Y
P
A
V
K
M
K
Y
A
E
N
V
P
H
N
Frog
Xenopus laevis
NP_001080277
532
59910
G179
D
V
R
P
Q
T
D
G
C
N
G
L
R
Y
N
Zebra Danio
Brachydanio rerio
NP_001004596
550
62395
Y207
Y
P
T
V
K
Q
K
Y
A
E
N
V
P
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960E8
585
66321
H207
Y
P
A
V
K
R
K
H
F
E
N
V
P
A
K
Honey Bee
Apis mellifera
XP_623390
563
64488
H207
Y
P
A
V
K
R
K
H
Q
E
N
V
P
H
K
Nematode Worm
Caenorhab. elegans
NP_499880
532
61378
G192
A
N
I
V
Q
Q
E
G
T
N
G
V
R
L
N
Sea Urchin
Strong. purpuratus
XP_798784
547
61424
V210
I
F
R
I
Y
P
A
V
R
K
K
H
L
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9P5N7
663
73012
F244
H
E
Q
V
Q
L
I
F
Q
Q
H
P
L
V
K
Conservation
Percent
Protein Identity:
100
99.6
84.8
98.1
N.A.
97
91.2
N.A.
51.2
89.4
79.7
76.7
N.A.
43.5
49
30.4
51.2
Protein Similarity:
100
99.8
88.3
98.9
N.A.
98.3
92.8
N.A.
53.2
94.1
88.5
88.5
N.A.
62.5
70.5
51
73.7
P-Site Identity:
100
100
86.6
100
N.A.
93.3
6.6
N.A.
0
100
6.6
86.6
N.A.
66.6
73.3
20
0
P-Site Similarity:
100
100
86.6
100
N.A.
93.3
26.6
N.A.
0
100
26.6
86.6
N.A.
73.3
80
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
39.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
47
0
0
0
7
0
47
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
0
0
0
7
0
0
60
0
0
0
7
0
% E
% Phe:
0
7
0
0
0
0
0
7
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
20
0
0
20
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
14
0
0
7
7
0
54
0
% H
% Ile:
7
0
7
7
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
60
0
60
0
0
7
7
0
0
0
20
% K
% Leu:
0
0
0
0
0
7
0
0
0
0
0
14
14
7
0
% L
% Met:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
20
54
0
0
0
67
% N
% Pro:
0
60
0
14
0
7
0
0
0
0
0
7
60
0
0
% P
% Gln:
0
0
7
0
27
14
0
0
14
7
0
0
0
0
0
% Q
% Arg:
0
0
20
0
0
14
0
0
7
0
0
0
20
0
0
% R
% Ser:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% S
% Thr:
0
0
14
0
0
14
0
0
7
0
7
0
0
0
0
% T
% Val:
0
14
0
74
0
0
0
7
0
0
0
67
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
0
0
7
0
0
47
0
0
0
0
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _