Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX2 All Species: 32.73
Human Site: S98 Identified Species: 60
UniProt: P32856 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P32856 NP_001971.2 288 33341 S98 K L K A I E Q S F D Q D E S G
Chimpanzee Pan troglodytes XP_001138080 288 33353 S98 K L K A I E Q S F D Q D E S G
Rhesus Macaque Macaca mulatta XP_001111568 383 42313 S193 K L K A I E Q S F D Q D E S G
Dog Lupus familis XP_534637 338 37747 S148 K L K S I E Q S F D Q D E S G
Cat Felis silvestris
Mouse Mus musculus Q00262 289 33159 S99 K L K S I E Q S C D Q D E N G
Rat Rattus norvegicus P50279 290 33341 S100 K L K A I E Q S C D Q D E N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233551 316 35842 S127 K L K S I E Q S I E Q E E G L
Frog Xenopus laevis NP_001086863 290 33138 T99 K L K S I A Q T I H Q D E S A
Zebra Danio Brachydanio rerio NP_571598 288 33347 S98 K L K A I E Q S I E Q E E G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24547 291 33630 N102 K L K G I E Q N I E Q E E Q Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O16000 291 33234 N100 G K L K L I E N A I D H D E Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64791 303 34450 A104 K L E A L E K A N A N S R N V
Baker's Yeast Sacchar. cerevisiae P32867 290 33088 L94 A T D L Q F K L K N E I K S A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 69.7 77.2 N.A. 88.9 87.9 N.A. N.A. 59.4 73.4 62.8 N.A. 60.1 N.A. 53.9 N.A.
Protein Similarity: 100 99.6 72 81 N.A. 95.1 94.4 N.A. N.A. 72.4 86.5 80.9 N.A. 75.2 N.A. 71.1 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 80 86.6 N.A. N.A. 60 60 66.6 N.A. 53.3 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 80 73.3 80 N.A. 73.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.1 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. 45.8 52.4 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 47 0 8 0 8 8 8 0 0 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 47 8 54 8 0 0 % D
% Glu: 0 0 8 0 0 77 8 0 0 24 8 24 77 8 0 % E
% Phe: 0 0 0 0 0 8 0 0 31 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 0 0 0 0 0 0 0 0 0 16 47 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % H
% Ile: 0 0 0 0 77 8 0 0 31 8 0 8 0 0 0 % I
% Lys: 85 8 77 8 0 0 16 0 8 0 0 0 8 0 0 % K
% Leu: 0 85 8 8 16 0 0 8 0 0 0 0 0 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 16 8 8 8 0 0 24 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 77 0 0 0 77 0 0 8 16 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 0 0 0 31 0 0 0 62 0 0 0 8 0 47 0 % S
% Thr: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _