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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX2
All Species:
35.45
Human Site:
Y242
Identified Species:
65
UniProt:
P32856
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32856
NP_001971.2
288
33341
Y242
N
V
M
N
A
T
D
Y
V
E
H
A
K
E
E
Chimpanzee
Pan troglodytes
XP_001138080
288
33353
Y242
N
V
M
N
A
T
D
Y
V
E
H
A
K
E
E
Rhesus Macaque
Macaca mulatta
XP_001111568
383
42313
Y337
N
I
M
N
A
T
D
Y
V
E
H
A
K
E
E
Dog
Lupus familis
XP_534637
338
37747
Y292
N
V
M
N
A
T
D
Y
V
E
H
A
K
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q00262
289
33159
Y243
N
V
V
N
S
V
D
Y
V
E
H
A
K
E
E
Rat
Rattus norvegicus
P50279
290
33341
Y244
N
V
V
N
S
V
D
Y
V
E
H
A
K
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233551
316
35842
Y271
N
V
E
H
S
V
D
Y
V
E
R
A
V
S
D
Frog
Xenopus laevis
NP_001086863
290
33138
Y243
N
V
E
N
A
A
E
Y
I
E
H
A
K
E
E
Zebra Danio
Brachydanio rerio
NP_571598
288
33347
Y242
N
V
E
H
S
V
D
Y
V
E
R
A
V
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Y246
H
V
E
H
A
M
D
Y
V
Q
T
A
T
Q
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
F244
N
V
E
H
A
K
E
F
V
D
R
A
V
A
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64791
303
34450
F254
H
V
S
K
A
S
S
F
V
R
R
G
T
D
Q
Baker's Yeast
Sacchar. cerevisiae
P32867
290
33088
D241
N
V
E
D
A
Q
L
D
V
E
Q
G
V
G
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
69.7
77.2
N.A.
88.9
87.9
N.A.
N.A.
59.4
73.4
62.8
N.A.
60.1
N.A.
53.9
N.A.
Protein Similarity:
100
99.6
72
81
N.A.
95.1
94.4
N.A.
N.A.
72.4
86.5
80.9
N.A.
75.2
N.A.
71.1
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
80
80
N.A.
N.A.
46.6
73.3
46.6
N.A.
40
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
66.6
86.6
66.6
N.A.
73.3
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.8
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
70
8
0
0
0
0
0
85
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
70
8
0
8
0
0
0
8
31
% D
% Glu:
0
0
47
0
0
0
16
0
0
77
0
0
0
54
54
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
16
0
8
0
% G
% His:
16
0
0
31
0
0
0
0
0
0
54
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
0
0
0
0
0
0
54
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
31
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
85
0
0
54
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
8
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
31
0
0
0
0
% R
% Ser:
0
0
8
0
31
8
8
0
0
0
0
0
0
16
0
% S
% Thr:
0
0
0
0
0
31
0
0
0
0
8
0
16
0
0
% T
% Val:
0
93
16
0
0
31
0
0
93
0
0
0
31
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _