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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX2
All Species:
50.61
Human Site:
Y256
Identified Species:
92.78
UniProt:
P32856
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32856
NP_001971.2
288
33341
Y256
E
T
K
K
A
I
K
Y
Q
S
K
A
R
R
K
Chimpanzee
Pan troglodytes
XP_001138080
288
33353
Y256
E
T
K
K
A
I
K
Y
Q
S
K
A
R
R
K
Rhesus Macaque
Macaca mulatta
XP_001111568
383
42313
Y351
E
T
K
K
A
I
K
Y
Q
S
K
A
R
R
K
Dog
Lupus familis
XP_534637
338
37747
Y306
E
T
K
K
A
I
K
Y
H
S
K
A
R
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q00262
289
33159
Y257
E
T
K
K
A
I
K
Y
Q
S
K
A
R
R
K
Rat
Rattus norvegicus
P50279
290
33341
Y258
E
T
K
K
A
I
K
Y
Q
S
K
A
R
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233551
316
35842
Y285
D
T
K
K
A
V
K
Y
Q
S
K
A
R
R
K
Frog
Xenopus laevis
NP_001086863
290
33138
Y257
E
T
K
K
A
V
K
Y
Q
S
K
S
R
R
K
Zebra Danio
Brachydanio rerio
NP_571598
288
33347
Y256
D
T
K
K
A
V
K
Y
Q
S
Q
A
R
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Y260
D
T
K
K
A
L
K
Y
Q
S
K
A
R
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
Y258
D
T
K
K
A
V
Q
Y
Q
S
K
A
R
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64791
303
34450
Y268
Q
L
Q
D
A
R
E
Y
Q
K
S
S
R
K
W
Baker's Yeast
Sacchar. cerevisiae
P32867
290
33088
S255
H
T
D
K
A
V
K
S
A
R
K
A
R
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
69.7
77.2
N.A.
88.9
87.9
N.A.
N.A.
59.4
73.4
62.8
N.A.
60.1
N.A.
53.9
N.A.
Protein Similarity:
100
99.6
72
81
N.A.
95.1
94.4
N.A.
N.A.
72.4
86.5
80.9
N.A.
75.2
N.A.
71.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
86.6
86.6
73.3
N.A.
86.6
N.A.
80
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.8
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
100
0
0
0
8
0
0
85
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
54
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
85
93
0
0
85
0
0
8
85
0
0
24
85
% K
% Leu:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
0
8
0
85
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
8
0
0
100
77
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
85
8
16
0
0
0
% S
% Thr:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
39
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _