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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTH
All Species:
41.52
Human Site:
Y194
Identified Species:
76.11
UniProt:
P32929
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32929
NP_001893.2
405
44508
Y194
D
N
T
F
M
S
P
Y
F
Q
R
P
L
A
L
Chimpanzee
Pan troglodytes
XP_513486
405
44534
Y194
D
N
T
F
M
S
P
Y
F
Q
R
P
L
A
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537115
405
44312
Y194
D
N
T
F
M
S
A
Y
F
Q
R
P
L
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN5
398
43549
Y193
D
N
T
F
M
S
A
Y
F
Q
R
P
L
A
L
Rat
Rattus norvegicus
P18757
398
43587
Y193
D
N
T
F
M
S
A
Y
F
Q
R
P
L
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422542
399
43880
Y188
D
N
S
F
M
S
A
Y
F
Q
R
P
L
S
L
Frog
Xenopus laevis
NP_001087988
398
43874
Y187
D
N
T
F
L
S
A
Y
F
Q
R
P
L
A
L
Zebra Danio
Brachydanio rerio
NP_997769
400
43830
Y193
D
N
T
F
M
S
A
Y
F
Q
R
P
L
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611352
393
42970
Y187
D
N
T
F
L
T
S
Y
F
Q
R
P
L
E
L
Honey Bee
Apis mellifera
XP_395917
381
41980
Q182
T
F
L
T
C
Y
Y
Q
K
P
L
K
L
G
A
Nematode Worm
Caenorhab. elegans
P55216
392
43076
Y185
D
N
T
F
M
S
P
Y
F
Q
R
P
I
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53780
464
50411
V260
D
N
S
I
M
S
P
V
L
S
R
P
L
E
L
Baker's Yeast
Sacchar. cerevisiae
P31373
394
42524
Y186
D
N
T
F
L
S
P
Y
I
S
N
P
L
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
89.6
N.A.
84.4
83.6
N.A.
N.A.
76.7
75.3
75.5
N.A.
60.2
56
57.5
N.A.
Protein Similarity:
100
99.5
N.A.
94.3
N.A.
90.1
89.6
N.A.
N.A.
86.9
87.1
86.1
N.A.
75.3
71.5
73.8
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
86.6
93.3
N.A.
73.3
6.6
86.6
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
86.6
6.6
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
49.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.8
67.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
47
0
0
0
0
0
0
54
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
93
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% E
% Phe:
0
8
0
85
0
0
0
0
77
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% K
% Leu:
0
0
8
0
24
0
0
0
8
0
8
0
93
0
85
% L
% Met:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
93
0
0
0
0
0
0
0
0
8
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
39
0
0
8
0
93
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
77
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
85
0
0
0
0
% R
% Ser:
0
0
16
0
0
85
8
0
0
16
0
0
0
16
0
% S
% Thr:
8
0
77
8
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _