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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTH
All Species:
13.64
Human Site:
Y60
Identified Species:
25
UniProt:
P32929
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32929
NP_001893.2
405
44508
Y60
G
Q
H
S
G
F
E
Y
S
R
S
G
N
P
T
Chimpanzee
Pan troglodytes
XP_513486
405
44534
Y60
G
Q
H
S
G
F
E
Y
S
R
S
G
N
P
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537115
405
44312
Y60
G
Q
H
A
G
F
E
Y
S
R
S
G
N
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN5
398
43549
S60
Q
S
S
G
F
E
Y
S
R
S
G
N
P
T
R
Rat
Rattus norvegicus
P18757
398
43587
S60
Q
S
S
G
F
V
Y
S
R
S
G
N
P
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422542
399
43880
P60
D
Y
S
R
C
G
N
P
T
R
T
C
L
E
K
Frog
Xenopus laevis
NP_001087988
398
43874
E65
N
P
T
R
N
S
M
E
K
A
V
A
A
L
D
Zebra Danio
Brachydanio rerio
NP_997769
400
43830
R60
H
A
G
F
E
Y
S
R
S
G
N
P
T
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611352
393
42970
C66
T
R
N
V
L
E
T
C
F
A
A
L
D
N
A
Honey Bee
Apis mellifera
XP_395917
381
41980
T60
P
T
R
N
V
L
Q
T
C
L
A
A
L
E
D
Nematode Worm
Caenorhab. elegans
P55216
392
43076
L60
G
N
P
T
R
D
V
L
Q
K
N
L
A
A
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53780
464
50411
Y127
I
E
N
G
P
Y
D
Y
T
R
S
G
N
P
T
Baker's Yeast
Sacchar. cerevisiae
P31373
394
42524
E62
N
P
N
R
E
N
L
E
R
A
V
A
A
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
89.6
N.A.
84.4
83.6
N.A.
N.A.
76.7
75.3
75.5
N.A.
60.2
56
57.5
N.A.
Protein Similarity:
100
99.5
N.A.
94.3
N.A.
90.1
89.6
N.A.
N.A.
86.9
87.1
86.1
N.A.
75.3
71.5
73.8
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
0
0
N.A.
N.A.
6.6
0
6.6
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
0
0
N.A.
N.A.
20
0
20
N.A.
26.6
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
49.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.8
67.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
0
24
16
24
24
8
8
% A
% Cys:
0
0
0
0
8
0
0
8
8
0
0
8
0
0
0
% C
% Asp:
8
0
0
0
0
8
8
0
0
0
0
0
8
0
16
% D
% Glu:
0
8
0
0
16
16
24
16
0
0
0
0
0
16
8
% E
% Phe:
0
0
0
8
16
24
0
0
8
0
0
0
0
0
0
% F
% Gly:
31
0
8
24
24
8
0
0
0
8
16
31
0
0
0
% G
% His:
8
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% K
% Leu:
0
0
0
0
8
8
8
8
0
8
0
16
16
16
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
16
8
24
8
8
8
8
0
0
0
16
16
31
8
8
% N
% Pro:
8
16
8
0
8
0
0
8
0
0
0
8
16
31
0
% P
% Gln:
16
24
0
0
0
0
8
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
8
24
8
0
0
8
24
39
0
0
0
8
16
% R
% Ser:
0
16
24
16
0
8
8
16
31
16
31
0
0
0
0
% S
% Thr:
8
8
8
8
0
0
8
8
16
0
8
0
8
16
31
% T
% Val:
0
0
0
8
8
8
8
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
16
16
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _