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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MC5R
All Species:
21.21
Human Site:
S227
Identified Species:
51.85
UniProt:
P33032
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33032
NP_005904.1
325
36601
S227
A
A
L
P
G
A
S
S
A
R
Q
R
T
S
M
Chimpanzee
Pan troglodytes
Q9TT23
325
36628
S227
A
A
L
P
R
A
S
S
A
R
Q
R
T
S
M
Rhesus Macaque
Macaca mulatta
Q864J4
317
34745
Q219
A
R
A
C
Q
H
A
Q
G
I
A
R
L
H
K
Dog
Lupus familis
XP_541099
632
70219
S534
A
A
L
R
G
C
S
S
V
R
Q
T
A
S
M
Cat
Felis silvestris
Mouse
Mus musculus
P41149
325
36935
S227
A
A
S
P
R
Y
N
S
V
R
Q
R
T
S
M
Rat
Rattus norvegicus
P35345
325
37032
S227
A
A
S
P
R
Y
N
S
V
R
Q
R
A
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518840
351
39301
S253
A
A
L
P
G
S
G
S
V
R
Q
R
T
S
M
Chicken
Gallus gallus
P55167
314
35279
R217
A
L
A
C
H
H
V
R
S
I
S
S
Q
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_775386
316
35818
P216
V
K
R
I
A
A
L
P
G
Y
N
S
I
H
Q
Tiger Blowfish
Takifugu rubipres
NP_001027937
340
38347
S238
A
A
L
P
G
S
N
S
I
H
Q
R
A
S
M
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
45.5
44.4
N.A.
80.3
81.2
N.A.
70.6
48.3
N.A.
71.6
69.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
62.1
47.3
N.A.
87.6
88.6
N.A.
80.3
68.6
N.A.
81.2
80.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
13.3
66.6
N.A.
66.6
60
N.A.
80
6.6
N.A.
6.6
66.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
20
66.6
N.A.
73.3
66.6
N.A.
86.6
13.3
N.A.
6.6
80
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
90
70
20
0
10
30
10
0
20
0
10
0
30
0
0
% A
% Cys:
0
0
0
20
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
40
0
10
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
20
0
0
0
10
0
0
0
20
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
20
0
0
10
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
20
% K
% Leu:
0
10
50
0
0
0
10
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% M
% Asn:
0
0
0
0
0
0
30
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
60
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
70
0
10
10
10
% Q
% Arg:
0
10
10
10
30
0
0
10
0
60
0
70
0
0
0
% R
% Ser:
0
0
20
0
0
20
30
70
10
0
10
20
0
70
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
40
0
0
% T
% Val:
10
0
0
0
0
0
10
0
40
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
20
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _