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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MC5R
All Species:
27.27
Human Site:
T143
Identified Species:
66.67
UniProt:
P33032
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33032
NP_005904.1
325
36601
T143
I
A
V
D
R
Y
V
T
I
F
Y
A
L
R
Y
Chimpanzee
Pan troglodytes
Q9TT23
325
36628
T143
I
A
V
D
R
Y
V
T
I
F
Y
A
L
R
Y
Rhesus Macaque
Macaca mulatta
Q864J4
317
34745
L135
M
L
S
S
L
C
F
L
G
A
I
A
V
D
R
Dog
Lupus familis
XP_541099
632
70219
T450
I
A
V
D
R
Y
V
T
I
F
Y
A
L
R
Y
Cat
Felis silvestris
Mouse
Mus musculus
P41149
325
36935
T143
I
A
V
D
R
Y
I
T
I
F
Y
A
L
R
Y
Rat
Rattus norvegicus
P35345
325
37032
T143
I
A
V
D
R
Y
I
T
I
F
Y
A
L
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518840
351
39301
T169
I
A
V
D
R
Y
I
T
I
F
Y
A
L
R
Y
Chicken
Gallus gallus
P55167
314
35279
L133
V
V
S
S
L
S
F
L
G
V
I
A
V
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_775386
316
35818
D132
S
L
L
A
I
A
V
D
R
Y
V
T
I
F
Y
Tiger Blowfish
Takifugu rubipres
NP_001027937
340
38347
T154
I
A
V
D
R
Y
V
T
I
F
Y
A
L
R
Y
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
45.5
44.4
N.A.
80.3
81.2
N.A.
70.6
48.3
N.A.
71.6
69.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
62.1
47.3
N.A.
87.6
88.6
N.A.
80.3
68.6
N.A.
81.2
80.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
93.3
93.3
N.A.
93.3
6.6
N.A.
13.3
100
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
20
N.A.
33.3
100
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
0
10
0
10
0
0
0
10
0
90
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
70
0
0
0
10
0
0
0
0
0
20
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
20
0
0
70
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
70
0
0
0
10
0
30
0
70
0
20
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
20
10
0
20
0
0
20
0
0
0
0
70
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
70
0
0
0
10
0
0
0
0
70
20
% R
% Ser:
10
0
20
20
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
70
0
0
0
10
0
0
0
% T
% Val:
10
10
70
0
0
0
50
0
0
10
10
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
70
0
0
0
10
70
0
0
0
80
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _