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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIITA
All Species:
11.82
Human Site:
S280
Identified Species:
32.5
UniProt:
P33076
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33076
NP_000237.2
1130
123443
S280
T
V
H
G
L
P
T
S
P
D
R
P
G
S
T
Chimpanzee
Pan troglodytes
Q53B87
1040
115280
G277
Q
K
S
P
A
T
L
G
L
E
E
L
F
S
T
Rhesus Macaque
Macaca mulatta
XP_001103518
1130
123636
S280
T
V
H
G
L
P
T
S
P
D
R
P
G
S
T
Dog
Lupus familis
XP_547128
1104
119761
A272
T
S
P
F
A
P
S
A
A
D
L
P
G
M
P
Cat
Felis silvestris
Mouse
Mus musculus
P79621
1155
127510
S306
S
I
P
S
L
P
E
S
P
D
R
P
G
S
T
Rat
Rattus norvegicus
NP_445981
1153
127283
S306
T
V
P
S
L
P
E
S
P
D
R
P
G
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516927
965
106480
F207
S
G
P
G
D
R
E
F
G
V
T
W
E
S
R
Chicken
Gallus gallus
XP_425250
824
93504
M66
E
A
F
C
T
S
L
M
D
Y
F
R
D
V
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001343072
1044
115802
Q270
M
R
G
G
M
G
M
Q
S
H
Y
V
D
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.7
94.3
77.1
N.A.
61.3
61.3
N.A.
37.7
34.2
N.A.
32.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.2
96.6
84.3
N.A.
72.2
71.4
N.A.
52.1
47.4
N.A.
48.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
33.3
N.A.
66.6
80
N.A.
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
46.6
N.A.
80
80
N.A.
20
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
23
0
0
12
12
0
0
0
0
12
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
0
0
12
0
0
0
12
56
0
0
23
0
0
% D
% Glu:
12
0
0
0
0
0
34
0
0
12
12
0
12
0
0
% E
% Phe:
0
0
12
12
0
0
0
12
0
0
12
0
12
0
0
% F
% Gly:
0
12
12
45
0
12
0
12
12
0
0
0
56
0
0
% G
% His:
0
0
23
0
0
0
0
0
0
12
0
0
0
0
12
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
45
0
23
0
12
0
12
12
0
0
0
% L
% Met:
12
0
0
0
12
0
12
12
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
45
12
0
56
0
0
45
0
0
56
0
0
12
% P
% Gln:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
12
0
0
0
0
45
12
0
0
12
% R
% Ser:
23
12
12
23
0
12
12
45
12
0
0
0
0
67
0
% S
% Thr:
45
0
0
0
12
12
23
0
0
0
12
0
0
0
56
% T
% Val:
0
34
0
0
0
0
0
0
0
12
0
12
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _