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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDH5
All Species:
9.09
Human Site:
S683
Identified Species:
25
UniProt:
P33151
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33151
NP_001786.2
784
87516
S683
P
A
L
D
A
R
P
S
L
Y
A
Q
V
Q
K
Chimpanzee
Pan troglodytes
XP_523383
869
96866
S768
P
A
L
D
A
R
P
S
L
Y
A
Q
V
Q
K
Rhesus Macaque
Macaca mulatta
XP_001082385
785
87425
S684
P
A
L
D
A
R
P
S
L
Y
A
Q
V
Q
K
Dog
Lupus familis
XP_546894
772
86269
G691
P
A
V
H
A
G
P
G
E
M
A
A
M
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P55284
784
87884
A683
S
T
M
D
A
R
P
A
V
Y
T
Q
V
Q
K
Rat
Rattus norvegicus
P55280
789
88322
F714
D
N
T
D
V
R
D
F
I
S
Q
R
L
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8QGH3
798
89138
E701
N
R
Q
D
M
L
P
E
I
E
S
L
S
R
Y
Frog
Xenopus laevis
Q91838
790
88487
E694
T
R
Q
D
M
K
P
E
I
E
S
L
S
R
Y
Zebra Danio
Brachydanio rerio
NP_571289
800
88914
E703
P
R
K
D
M
K
P
E
L
Q
Y
G
M
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
98.2
79.3
N.A.
75.5
40.1
N.A.
N.A.
41.5
38.4
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90
98.8
88.7
N.A.
85.9
58.5
N.A.
N.A.
58.5
56.9
57.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
33.3
N.A.
60
20
N.A.
N.A.
13.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
80
46.6
N.A.
N.A.
33.3
40
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
45
0
0
56
0
0
12
0
0
45
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
89
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
34
12
23
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
12
0
0
0
12
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
34
0
0
0
0
12
0
% I
% Lys:
0
0
12
0
0
23
0
0
0
0
0
0
0
0
56
% K
% Leu:
0
0
34
0
0
12
0
0
45
0
0
23
12
0
0
% L
% Met:
0
0
12
0
34
0
0
0
0
12
0
0
23
0
0
% M
% Asn:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
56
0
0
0
0
0
89
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
23
0
0
0
0
0
0
12
12
45
0
45
0
% Q
% Arg:
0
34
0
0
0
56
0
0
0
0
0
12
0
45
0
% R
% Ser:
12
0
0
0
0
0
0
34
0
12
23
0
23
0
0
% S
% Thr:
12
12
12
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
12
0
12
0
0
0
12
0
0
0
45
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
45
12
0
0
0
23
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _