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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5B All Species: 22.73
Human Site: S908 Identified Species: 35.71
UniProt: P33176 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33176 NP_004512.1 963 109685 S908 R I K E A V R S K N M A R R G
Chimpanzee Pan troglodytes XP_507730 963 109724 S908 R I K E A V R S K N M A R R G
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 R812 D R I K E A V R A K N M A R R
Dog Lupus familis XP_535154 963 109729 S908 R I K E A V R S K N M A R R G
Cat Felis silvestris
Mouse Mus musculus Q61768 963 109531 S908 R I K E A V R S K N M A R R G
Rat Rattus norvegicus Q2PQA9 963 109512 S908 R I K E A V R S K N M A R R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 S908 R I K E A V R S K N M A R R G
Chicken Gallus gallus Q90640 1225 138905 L1141 D S E G S F K L E D L R D V T
Frog Xenopus laevis Q91784 1226 138905 C1084 S K K L T S K C S C K A R C G
Zebra Danio Brachydanio rerio XP_002664065 959 109002 A904 R I K E A V R A K N M A R R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 R923 R Y Q Y E V D R I K E A V R Q
Honey Bee Apis mellifera XP_395236 988 112484 Q930 R I K E A V R Q K N L A R R G
Nematode Worm Caenorhab. elegans P34540 815 91875 E767 E R K K Y Q Q E V E R I K E A
Sea Urchin Strong. purpuratus P35978 1031 117504 Q905 R I R E A V R Q R N F A K R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 A863 A V K D R L E A A K A G S T R
Conservation
Percent
Protein Identity: 100 99.9 64.6 98.5 N.A. 96.4 97.3 N.A. 96.7 25 26.2 86.2 N.A. 61.3 62.6 44.7 61
Protein Similarity: 100 99.9 74.6 99.2 N.A. 98.2 98.7 N.A. 98.1 44.4 44.1 92.8 N.A. 77.1 77.8 61.8 75.6
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 100 0 26.6 93.3 N.A. 26.6 86.6 6.6 66.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 40 33.3 100 N.A. 33.3 93.3 26.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 35.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 54.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 60 7 0 14 14 0 7 74 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 7 0 7 0 0 0 7 0 % C
% Asp: 14 0 0 7 0 0 7 0 0 7 0 0 7 0 0 % D
% Glu: 7 0 7 60 14 0 7 7 7 7 7 0 0 7 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 67 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 60 7 0 0 0 0 0 7 0 0 7 0 0 0 % I
% Lys: 0 7 74 14 0 0 14 0 54 20 7 0 14 0 0 % K
% Leu: 0 0 0 7 0 7 0 7 0 0 14 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 47 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 60 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 7 7 14 0 0 0 0 0 0 7 % Q
% Arg: 67 14 7 0 7 0 60 14 7 0 7 7 60 74 14 % R
% Ser: 7 7 0 0 7 7 0 40 7 0 0 0 7 0 0 % S
% Thr: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 7 % T
% Val: 0 7 0 0 0 67 7 0 7 0 0 0 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _