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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5B All Species: 27.27
Human Site: T182 Identified Species: 42.86
UniProt: P33176 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33176 NP_004512.1 963 109685 T182 S P D E V M D T I D E G K S N
Chimpanzee Pan troglodytes XP_507730 963 109724 T182 S P D E V M D T I D E G K S N
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 G149 V S K T G A E G A V L D E A K
Dog Lupus familis XP_535154 963 109729 T182 S P D E V M D T I D E G K S N
Cat Felis silvestris
Mouse Mus musculus Q61768 963 109531 T182 S P D E V M D T I D E G K S N
Rat Rattus norvegicus Q2PQA9 963 109512 T182 S P D E V M D T I D E G K S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 T182 S P D E V M D T I D E G K S N
Chicken Gallus gallus Q90640 1225 138905 C191 S A R D T V S C L E Q G N N C
Frog Xenopus laevis Q91784 1226 138905 C190 T A L D T L S C L E Q G N S S
Zebra Danio Brachydanio rerio XP_002664065 959 109002 T182 S P E E V M D T I D E G K S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 V189 S P E D V F E V I E E G K S N
Honey Bee Apis mellifera XP_395236 988 112484 V193 S P E E V F E V I E E G K S N
Nematode Worm Caenorhab. elegans P34540 815 91875 D104 T M E G V I G D N G L S G I I
Sea Urchin Strong. purpuratus P35978 1031 117504 V181 S P E E V M D V I E E G K S N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 V186 S V Q E V Y E V M R R G G N A
Conservation
Percent
Protein Identity: 100 99.9 64.6 98.5 N.A. 96.4 97.3 N.A. 96.7 25 26.2 86.2 N.A. 61.3 62.6 44.7 61
Protein Similarity: 100 99.9 74.6 99.2 N.A. 98.2 98.7 N.A. 98.1 44.4 44.1 92.8 N.A. 77.1 77.8 61.8 75.6
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 100 13.3 13.3 93.3 N.A. 60 66.6 6.6 80
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 100 53.3 60 100 N.A. 86.6 86.6 26.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 35.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 54.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 0 0 7 0 0 7 0 0 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 7 % C
% Asp: 0 0 40 20 0 0 54 7 0 47 0 7 0 0 0 % D
% Glu: 0 0 34 67 0 0 27 0 0 34 67 0 7 0 0 % E
% Phe: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 7 0 7 7 0 7 0 87 14 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 67 0 0 0 0 7 7 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 0 67 0 7 % K
% Leu: 0 0 7 0 0 7 0 0 14 0 14 0 0 0 0 % L
% Met: 0 7 0 0 0 54 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 0 0 14 14 67 % N
% Pro: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 14 0 0 0 0 % Q
% Arg: 0 0 7 0 0 0 0 0 0 7 7 0 0 0 0 % R
% Ser: 80 7 0 0 0 0 14 0 0 0 0 7 0 74 7 % S
% Thr: 14 0 0 7 14 0 0 47 0 0 0 0 0 0 0 % T
% Val: 7 7 0 0 80 7 0 27 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _