Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5B All Species: 35.15
Human Site: T219 Identified Species: 55.24
UniProt: P33176 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33176 NP_004512.1 963 109685 T219 V K Q E N T Q T E Q K L S G K
Chimpanzee Pan troglodytes XP_507730 963 109724 T219 V K Q E N T Q T E Q K L S G K
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 K186 H V P Y R D S K M T R I L Q D
Dog Lupus familis XP_535154 963 109729 T219 V K Q E N T Q T E Q K L S G K
Cat Felis silvestris
Mouse Mus musculus Q61768 963 109531 T219 V K Q E N T Q T E Q K L S G K
Rat Rattus norvegicus Q2PQA9 963 109512 T219 V K Q E N T Q T E Q K L S G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 T219 V K Q E N T Q T E Q K L S G K
Chicken Gallus gallus Q90640 1225 138905 D228 I D Q K K K N D K N S S F H S
Frog Xenopus laevis Q91784 1226 138905 D227 I E Q R K E G D K N N S F R S
Zebra Danio Brachydanio rerio XP_002664065 959 109002 T219 V K Q E N T Q T E Q K L S G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 N226 V K Q E N L E N Q K K L S G K
Honey Bee Apis mellifera XP_395236 988 112484 N230 V K Q E N L E N Q K K L S G K
Nematode Worm Caenorhab. elegans P34540 815 91875 Y141 K V S Y Y E I Y N E K I R D L
Sea Urchin Strong. purpuratus P35978 1031 117504 T218 V K Q E N M E T K K K L S G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 T223 I T Q K N V E T G S A K S G Q
Conservation
Percent
Protein Identity: 100 99.9 64.6 98.5 N.A. 96.4 97.3 N.A. 96.7 25 26.2 86.2 N.A. 61.3 62.6 44.7 61
Protein Similarity: 100 99.9 74.6 99.2 N.A. 98.2 98.7 N.A. 98.1 44.4 44.1 92.8 N.A. 77.1 77.8 61.8 75.6
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 100 6.6 6.6 100 N.A. 66.6 66.6 6.6 73.3
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 26.6 26.6 100 N.A. 86.6 86.6 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 35.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 54.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 7 0 14 0 0 0 0 0 7 7 % D
% Glu: 0 7 0 67 0 14 27 0 47 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 7 0 0 0 0 74 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 20 0 0 0 0 0 7 0 0 0 0 14 0 0 0 % I
% Lys: 7 67 0 14 14 7 0 7 20 20 74 7 0 0 67 % K
% Leu: 0 0 0 0 0 14 0 0 0 0 0 67 7 0 7 % L
% Met: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 74 0 7 14 7 14 7 0 0 0 0 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 87 0 0 0 47 0 14 47 0 0 0 7 7 % Q
% Arg: 0 0 0 7 7 0 0 0 0 0 7 0 7 7 0 % R
% Ser: 0 0 7 0 0 0 7 0 0 7 7 14 74 0 14 % S
% Thr: 0 7 0 0 0 47 0 60 0 7 0 0 0 0 0 % T
% Val: 67 14 0 0 0 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 14 7 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _