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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5B
All Species:
27.88
Human Site:
T414
Identified Species:
43.81
UniProt:
P33176
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33176
NP_004512.1
963
109685
T414
I
G
V
I
G
N
F
T
D
A
E
R
R
K
C
Chimpanzee
Pan troglodytes
XP_507730
963
109724
T414
I
G
V
I
G
N
F
T
D
A
E
R
R
K
C
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
L376
I
Q
E
E
L
T
R
L
Q
I
E
N
E
A
A
Dog
Lupus familis
XP_535154
963
109729
T414
I
G
V
T
G
N
F
T
D
A
E
R
R
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q61768
963
109531
T414
V
G
M
A
G
S
F
T
D
A
E
R
R
K
C
Rat
Rattus norvegicus
Q2PQA9
963
109512
T414
I
G
M
A
G
S
F
T
D
A
E
R
R
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
T414
I
G
V
T
G
N
F
T
D
A
E
R
R
K
C
Chicken
Gallus gallus
Q90640
1225
138905
S514
G
Q
V
T
K
R
S
S
D
D
F
T
T
Q
H
Frog
Xenopus laevis
Q91784
1226
138905
E456
Q
R
L
V
E
T
L
E
D
Q
E
L
K
D
N
Zebra Danio
Brachydanio rerio
XP_002664065
959
109002
T413
S
V
P
G
L
K
F
T
D
A
E
R
E
K
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
A430
A
N
M
S
A
S
V
A
V
N
E
Q
A
R
L
Honey Bee
Apis mellifera
XP_395236
988
112484
S431
N
L
M
A
G
S
L
S
N
E
E
R
Q
K
L
Nematode Worm
Caenorhab. elegans
P34540
815
91875
N331
A
R
A
K
T
I
K
N
V
V
Q
I
N
E
E
Sea Urchin
Strong. purpuratus
P35978
1031
117504
E410
E
E
K
N
K
W
E
E
E
K
V
K
L
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
A416
R
L
L
P
E
S
R
A
E
T
P
A
I
S
D
Conservation
Percent
Protein Identity:
100
99.9
64.6
98.5
N.A.
96.4
97.3
N.A.
96.7
25
26.2
86.2
N.A.
61.3
62.6
44.7
61
Protein Similarity:
100
99.9
74.6
99.2
N.A.
98.2
98.7
N.A.
98.1
44.4
44.1
92.8
N.A.
77.1
77.8
61.8
75.6
P-Site Identity:
100
100
13.3
93.3
N.A.
73.3
80
N.A.
93.3
13.3
13.3
53.3
N.A.
6.6
26.6
0
0
P-Site Similarity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
93.3
26.6
33.3
53.3
N.A.
33.3
60
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
54.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
20
7
0
0
14
0
47
0
7
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
47
% C
% Asp:
0
0
0
0
0
0
0
0
60
7
0
0
0
7
7
% D
% Glu:
7
7
7
7
14
0
7
14
14
7
74
0
14
7
14
% E
% Phe:
0
0
0
0
0
0
47
0
0
0
7
0
0
0
0
% F
% Gly:
7
40
0
7
47
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
40
0
0
14
0
7
0
0
0
7
0
7
7
0
0
% I
% Lys:
0
0
7
7
14
7
7
0
0
7
0
7
7
54
0
% K
% Leu:
0
14
14
0
14
0
14
7
0
0
0
7
7
0
14
% L
% Met:
0
0
27
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
7
0
27
0
7
7
7
0
7
7
0
7
% N
% Pro:
0
0
7
7
0
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
7
14
0
0
0
0
0
0
7
7
7
7
7
7
0
% Q
% Arg:
7
14
0
0
0
7
14
0
0
0
0
54
40
7
0
% R
% Ser:
7
0
0
7
0
34
7
14
0
0
0
0
0
7
0
% S
% Thr:
0
0
0
20
7
14
0
47
0
7
0
7
7
0
0
% T
% Val:
7
7
34
7
0
0
7
0
14
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _