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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5B
All Species:
50.3
Human Site:
Y277
Identified Species:
79.05
UniProt:
P33176
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33176
NP_004512.1
963
109685
Y277
E
G
S
T
Y
V
P
Y
R
D
S
K
M
T
R
Chimpanzee
Pan troglodytes
XP_507730
963
109724
Y277
E
G
S
T
Y
V
P
Y
R
D
S
K
M
T
R
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
T243
L
Q
Q
Q
L
T
V
T
M
W
S
K
K
A
S
Dog
Lupus familis
XP_535154
963
109729
Y277
E
G
S
T
Y
V
P
Y
R
D
S
K
M
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61768
963
109531
Y277
E
G
S
T
Y
V
P
Y
R
D
S
K
M
T
R
Rat
Rattus norvegicus
Q2PQA9
963
109512
Y277
E
G
S
T
Y
V
P
Y
R
D
S
K
M
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
Y277
E
S
S
T
Y
V
P
Y
R
D
S
K
M
T
R
Chicken
Gallus gallus
Q90640
1225
138905
Y290
K
K
G
G
F
V
P
Y
R
D
S
K
L
T
R
Frog
Xenopus laevis
Q91784
1226
138905
Y289
K
K
G
G
F
V
P
Y
R
D
S
K
L
T
R
Zebra Danio
Brachydanio rerio
XP_002664065
959
109002
Y277
E
A
T
T
Y
V
P
Y
R
D
S
K
M
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
Y285
G
N
K
T
H
I
P
Y
R
D
S
K
L
T
R
Honey Bee
Apis mellifera
XP_395236
988
112484
Y289
G
N
K
T
H
I
P
Y
R
D
S
K
L
T
R
Nematode Worm
Caenorhab. elegans
P34540
815
91875
T198
S
N
R
M
V
A
V
T
N
M
N
E
H
S
S
Sea Urchin
Strong. purpuratus
P35978
1031
117504
Y277
G
K
K
S
H
I
P
Y
R
D
S
K
M
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
Y282
G
K
S
S
H
V
P
Y
R
D
S
K
L
T
R
Conservation
Percent
Protein Identity:
100
99.9
64.6
98.5
N.A.
96.4
97.3
N.A.
96.7
25
26.2
86.2
N.A.
61.3
62.6
44.7
61
Protein Similarity:
100
99.9
74.6
99.2
N.A.
98.2
98.7
N.A.
98.1
44.4
44.1
92.8
N.A.
77.1
77.8
61.8
75.6
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
93.3
60
60
86.6
N.A.
60
60
0
60
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
93.3
80
80
93.3
N.A.
80
80
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
54.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
87
0
0
0
0
0
% D
% Glu:
47
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
27
34
14
14
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
27
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
14
27
20
0
0
0
0
0
0
0
0
94
7
0
0
% K
% Leu:
7
0
0
0
7
0
0
0
0
0
0
0
34
0
0
% L
% Met:
0
0
0
7
0
0
0
0
7
7
0
0
54
0
0
% M
% Asn:
0
20
0
0
0
0
0
0
7
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
87
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
7
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
0
87
0
0
0
0
0
87
% R
% Ser:
7
7
47
14
0
0
0
0
0
0
94
0
0
7
14
% S
% Thr:
0
0
7
60
0
7
0
14
0
0
0
0
0
87
0
% T
% Val:
0
0
0
0
7
67
14
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
47
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _