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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5B
All Species:
34.24
Human Site:
Y649
Identified Species:
53.81
UniProt:
P33176
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33176
NP_004512.1
963
109685
Y649
K
I
K
S
L
T
E
Y
L
Q
N
V
E
Q
K
Chimpanzee
Pan troglodytes
XP_507730
963
109724
Y649
K
I
K
S
L
T
E
Y
L
Q
N
V
E
Q
K
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
K590
V
S
F
Q
D
K
E
K
E
H
L
T
R
L
Q
Dog
Lupus familis
XP_535154
963
109729
Y649
K
I
K
S
L
T
E
Y
L
Q
N
V
E
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61768
963
109531
Y649
K
I
K
S
L
T
E
Y
L
Q
N
D
E
Q
K
Rat
Rattus norvegicus
Q2PQA9
963
109512
Y649
K
I
K
S
L
T
E
Y
L
Q
N
V
E
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
Y649
K
I
K
S
L
T
E
Y
L
Q
N
V
E
Q
K
Chicken
Gallus gallus
Q90640
1225
138905
V759
W
L
A
N
E
V
E
V
L
V
S
T
E
E
A
Frog
Xenopus laevis
Q91784
1226
138905
Q820
E
E
A
S
V
T
K
Q
I
E
S
L
E
T
E
Zebra Danio
Brachydanio rerio
XP_002664065
959
109002
Y647
K
I
K
S
L
S
E
Y
L
Q
N
I
E
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
S673
R
M
K
S
L
Q
E
S
M
R
E
A
E
N
K
Honey Bee
Apis mellifera
XP_395236
988
112484
S669
R
M
Q
T
L
T
E
S
M
K
V
A
E
A
R
Nematode Worm
Caenorhab. elegans
P34540
815
91875
S545
D
R
M
N
Q
A
T
S
L
L
N
A
H
L
D
Sea Urchin
Strong. purpuratus
P35978
1031
117504
N639
K
M
K
S
L
S
E
N
I
R
E
T
E
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
A635
F
S
A
A
S
S
D
A
E
A
R
K
R
A
E
Conservation
Percent
Protein Identity:
100
99.9
64.6
98.5
N.A.
96.4
97.3
N.A.
96.7
25
26.2
86.2
N.A.
61.3
62.6
44.7
61
Protein Similarity:
100
99.9
74.6
99.2
N.A.
98.2
98.7
N.A.
98.1
44.4
44.1
92.8
N.A.
77.1
77.8
61.8
75.6
P-Site Identity:
100
100
6.6
100
N.A.
93.3
100
N.A.
100
20
20
86.6
N.A.
40
26.6
13.3
46.6
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
100
N.A.
100
46.6
73.3
100
N.A.
66.6
73.3
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
54.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
7
0
7
0
7
0
7
0
20
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
0
7
0
0
0
0
7
0
0
7
% D
% Glu:
7
7
0
0
7
0
80
0
14
7
14
0
80
7
14
% E
% Phe:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% H
% Ile:
0
47
0
0
0
0
0
0
14
0
0
7
0
0
0
% I
% Lys:
54
0
60
0
0
7
7
7
0
7
0
7
0
0
60
% K
% Leu:
0
7
0
0
67
0
0
0
60
7
7
7
0
14
0
% L
% Met:
0
20
7
0
0
0
0
0
14
0
0
0
0
0
0
% M
% Asn:
0
0
0
14
0
0
0
7
0
0
54
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
7
7
7
0
7
0
47
0
0
0
47
7
% Q
% Arg:
14
7
0
0
0
0
0
0
0
14
7
0
14
0
7
% R
% Ser:
0
14
0
67
7
20
0
20
0
0
14
0
0
0
0
% S
% Thr:
0
0
0
7
0
54
7
0
0
0
0
20
0
7
0
% T
% Val:
7
0
0
0
7
7
0
7
0
7
7
34
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _