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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSTF2 All Species: 22.73
Human Site: S480 Identified Species: 45.45
UniProt: P33240 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33240 NP_001316.1 577 60959 S480 G P R G P I P S G M Q G P S P
Chimpanzee Pan troglodytes XP_529072 650 69012 S553 G P R G P I P S G M Q G P S P
Rhesus Macaque Macaca mulatta XP_001089558 577 60953 S480 G P R G P I P S G M Q G P S P
Dog Lupus familis XP_861405 577 60905 S480 G P R G P M P S G I Q G P S P
Cat Felis silvestris
Mouse Mus musculus Q8BIQ5 580 61323 S483 G P R G P M P S G I Q G P N P
Rat Rattus norvegicus NP_001124486 575 60820 S478 G P R G P I P S G I Q G P N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513073 1123 120959 P1026 M P G G I Q G P G G P I S M G
Chicken Gallus gallus NP_001006433 475 49873 G373 N P R G P M A G G I Q G P G P
Frog Xenopus laevis NP_001080179 518 54716 R421 D P R A L E P R G P G P V P G
Zebra Danio Brachydanio rerio NP_956408 488 51251 E391 E Q R G P P I E A R G R D P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623321 441 48118 P347 P V A P P V V P R P V V A P T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186020 679 70299 H582 G F E R G E P H G M G G M R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 99.6 96.3 N.A. 93.2 93.2 N.A. 42.7 66.3 63 62.5 N.A. N.A. 42.9 N.A. 43.1
Protein Similarity: 100 88.7 99.8 97.9 N.A. 96.2 95.8 N.A. 45.5 71.5 69.3 68.9 N.A. N.A. 55.6 N.A. 55
P-Site Identity: 100 100 100 86.6 N.A. 80 86.6 N.A. 20 60 26.6 20 N.A. N.A. 6.6 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 73.3 26.6 20 N.A. N.A. 13.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 0 9 0 9 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 9 0 9 0 0 17 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 59 0 9 75 9 0 9 9 84 9 25 67 0 9 17 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 34 9 0 0 34 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % L
% Met: 9 0 0 0 0 25 0 0 0 34 0 0 9 9 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % N
% Pro: 9 75 0 9 75 9 67 17 0 17 9 9 59 25 67 % P
% Gln: 0 9 0 0 0 9 0 0 0 0 59 0 0 0 0 % Q
% Arg: 0 0 75 9 0 0 0 9 9 9 0 9 0 9 9 % R
% Ser: 0 0 0 0 0 0 0 50 0 0 0 0 9 34 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % T
% Val: 0 9 0 0 0 9 9 0 0 0 9 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _