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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSTF2 All Species: 20.91
Human Site: S518 Identified Species: 41.82
UniProt: P33240 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33240 NP_001316.1 577 60959 S518 G A S I Q G G S Q P G G F S P
Chimpanzee Pan troglodytes XP_529072 650 69012 S591 G A S I Q G G S Q P G G F S P
Rhesus Macaque Macaca mulatta XP_001089558 577 60953 S518 G A S I Q G G S Q P G G F S P
Dog Lupus familis XP_861405 577 60905 G518 G A S I Q G G G Q P G G F S P
Cat Felis silvestris
Mouse Mus musculus Q8BIQ5 580 61323 S521 G A S M Q G G S Q P G G F S P
Rat Rattus norvegicus NP_001124486 575 60820 S516 G A S M Q G G S Q P G G F S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513073 1123 120959 G1064 V P G M Q G G G Q P G G F S P
Chicken Gallus gallus NP_001006433 475 49873 G411 G G G I P G A G V Q G A G Q P
Frog Xenopus laevis NP_001080179 518 54716 S459 V P G I Q G A S A Q G G F S P
Zebra Danio Brachydanio rerio NP_956408 488 51251 A429 P H G M G P G A P P P A R P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623321 441 48118 A385 S A T S R L M A G M S P A G N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186020 679 70299 A620 S T N L S Q L A Q N I N L S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 99.6 96.3 N.A. 93.2 93.2 N.A. 42.7 66.3 63 62.5 N.A. N.A. 42.9 N.A. 43.1
Protein Similarity: 100 88.7 99.8 97.9 N.A. 96.2 95.8 N.A. 45.5 71.5 69.3 68.9 N.A. N.A. 55.6 N.A. 55
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 66.6 33.3 60 13.3 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 73.3 33.3 60 26.6 N.A. N.A. 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 59 0 0 0 0 17 25 9 0 0 17 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % F
% Gly: 59 9 34 0 9 75 67 25 9 0 75 67 9 9 9 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 50 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 9 9 0 0 0 0 0 9 0 0 % L
% Met: 0 0 0 34 0 0 9 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 9 0 9 0 0 9 % N
% Pro: 9 17 0 0 9 9 0 0 9 67 9 9 0 9 75 % P
% Gln: 0 0 0 0 67 9 0 0 67 17 0 0 0 9 9 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 17 0 50 9 9 0 0 50 0 0 9 0 0 75 0 % S
% Thr: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 17 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _