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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUT All Species: 12.73
Human Site: S140 Identified Species: 25.45
UniProt: P33316 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33316 NP_001020419.1 252 26706 S140 A A G Y D L Y S A Y D Y T I P
Chimpanzee Pan troglodytes XP_523069 252 26703 S140 A A G Y D L Y S A Y D Y T I P
Rhesus Macaque Macaca mulatta XP_001113050 252 26682 S140 A A G Y D L Y S A Y D Y T I P
Dog Lupus familis XP_851889 214 23101 S126 D I Q V A L P S G C Y G R V A
Cat Felis silvestris
Mouse Mus musculus NP_076084 162 17366 S74 D I Q I A V P S G C Y G R V A
Rat Rattus norvegicus P70583 205 21984 S117 D I Q I A V P S G C Y G R V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509504 115 12475 S27 D I Q I S L P S G C Y G R V A
Chicken Gallus gallus NP_001072956 166 17778 A78 D I Q I A L P A G C Y G R V A
Frog Xenopus laevis NP_001091360 164 17673 P76 D I Q I S V P P G C Y G R V A
Zebra Danio Brachydanio rerio NP_001006005 187 20088 H99 G I Q I A V P H G Y Y G R V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33317 147 15289 V59 D I S F T V P V G T Y G R I A
Red Bread Mold Neurospora crassa Q6MVL2 165 17422 R77 T Y G R I A P R S G L A A K N
Conservation
Percent
Protein Identity: 100 90.8 87.3 71.8 N.A. 57.9 65 N.A. 42.4 59.1 53.1 50.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 91.6 89.2 75 N.A. 60.7 69.8 N.A. 44.8 62.2 59.9 62.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 6.6 6.6 N.A. 13.3 6.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 20 20 N.A. 20 20 13.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.9 39.2
Protein Similarity: N.A. N.A. N.A. N.A. 44.8 49.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 25 0 0 42 9 0 9 25 0 0 9 9 0 67 % A
% Cys: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % C
% Asp: 59 0 0 0 25 0 0 0 0 0 25 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 34 0 0 0 0 0 67 9 0 67 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 67 0 50 9 0 0 0 0 0 0 0 0 34 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 0 0 0 0 50 0 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 75 9 0 0 0 0 0 0 25 % P
% Gln: 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 9 0 0 0 0 67 0 0 % R
% Ser: 0 0 9 0 17 0 0 59 9 0 0 0 0 0 0 % S
% Thr: 9 0 0 0 9 0 0 0 0 9 0 0 25 0 0 % T
% Val: 0 0 0 9 0 42 0 9 0 0 0 0 0 59 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 25 0 0 25 0 0 34 67 25 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _