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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GUCY1A2 All Species: 0
Human Site: S10 Identified Species: 0
UniProt: P33402 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33402 NP_000846.1 732 81750 S10 R R K I S S E S F S S L G S D
Chimpanzee Pan troglodytes XP_522169 734 81883
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536590 746 83063
Cat Felis silvestris
Mouse Mus musculus Q9ERL9 691 77555
Rat Rattus norvegicus Q9WVI4 730 81768
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509082 1341 147755
Chicken Gallus gallus XP_001233954 724 80937
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002667138 626 69572
Tiger Blowfish Takifugu rubipres NP_001027855 675 75480
Fruit Fly Dros. melanogaster Q07093 676 75644
Honey Bee Apis mellifera NP_001011650 699 78655
Nematode Worm Caenorhab. elegans O02298 688 78384
Sea Urchin Strong. purpuratus P16065 1125 126238
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 93.6 N.A. 48.3 90.9 N.A. 48.3 88.3 N.A. 55 45.9 34.8 37 28.2 22.3
Protein Similarity: 100 99.7 N.A. 95.8 N.A. 62.9 94.8 N.A. 51.2 93.1 N.A. 67.2 62 53.1 54.3 46 36.7
P-Site Identity: 100 0 N.A. 0 N.A. 0 0 N.A. 0 0 N.A. 0 0 0 0 0 0
P-Site Similarity: 100 0 N.A. 0 N.A. 0 0 N.A. 0 0 N.A. 0 0 0 0 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % D
% Glu: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 100 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 100 100 0 100 0 100 100 0 0 100 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _