KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUCY1A2
All Species:
36.06
Human Site:
S441
Identified Species:
66.11
UniProt:
P33402
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33402
NP_000846.1
732
81750
S441
M
G
R
G
L
H
L
S
D
I
P
I
H
D
A
Chimpanzee
Pan troglodytes
XP_522169
734
81883
S443
M
G
R
G
L
H
L
S
D
I
P
I
H
D
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536590
746
83063
S455
M
G
R
G
L
H
L
S
D
I
P
I
H
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERL9
691
77555
S401
T
G
R
G
L
Y
L
S
D
I
P
I
H
N
A
Rat
Rattus norvegicus
Q9WVI4
730
81768
S439
I
G
R
G
L
H
L
S
D
I
P
I
H
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509082
1341
147755
S1051
M
G
R
G
L
H
L
S
D
I
P
I
H
D
A
Chicken
Gallus gallus
XP_001233954
724
80937
S433
M
G
R
G
L
H
L
S
D
I
P
I
H
D
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002667138
626
69572
T362
A
K
T
D
P
H
R
T
L
T
F
S
N
S
F
Tiger Blowfish
Takifugu rubipres
NP_001027855
675
75480
S407
T
G
R
G
L
Y
L
S
D
I
P
I
H
N
A
Fruit Fly
Dros. melanogaster
Q07093
676
75644
A404
V
I
L
V
G
E
Q
A
R
A
Q
D
G
L
R
Honey Bee
Apis mellifera
NP_001011650
699
78655
S411
T
G
R
G
L
F
I
S
D
I
P
L
H
D
A
Nematode Worm
Caenorhab. elegans
O02298
688
78384
D416
L
R
S
G
K
A
M
D
A
K
E
F
A
D
C
Sea Urchin
Strong. purpuratus
P16065
1125
126238
R773
I
L
T
E
L
Y
S
R
Q
E
P
F
H
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
93.6
N.A.
48.3
90.9
N.A.
48.3
88.3
N.A.
55
45.9
34.8
37
28.2
22.3
Protein Similarity:
100
99.7
N.A.
95.8
N.A.
62.9
94.8
N.A.
51.2
93.1
N.A.
67.2
62
53.1
54.3
46
36.7
P-Site Identity:
100
100
N.A.
100
N.A.
80
93.3
N.A.
100
100
N.A.
6.6
80
0
73.3
13.3
20
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
100
100
N.A.
20
93.3
13.3
86.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
8
8
8
0
0
8
0
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
8
0
0
0
8
70
0
0
8
0
62
0
% D
% Glu:
0
0
0
8
0
8
0
0
0
8
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
16
0
0
8
% F
% Gly:
0
70
0
77
8
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
54
0
0
0
0
0
0
77
0
0
% H
% Ile:
16
8
0
0
0
0
8
0
0
70
0
62
0
0
0
% I
% Lys:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
8
8
0
77
0
62
0
8
0
0
8
0
8
0
% L
% Met:
39
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
16
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
77
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% Q
% Arg:
0
8
70
0
0
0
8
8
8
0
0
0
0
0
8
% R
% Ser:
0
0
8
0
0
0
8
70
0
0
0
8
0
8
0
% S
% Thr:
24
0
16
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _