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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC1 All Species: 11.21
Human Site: T159 Identified Species: 22.42
UniProt: P33527 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33527 NP_004987.2 1531 171561 T159 I L R S K I M T A L K E D A Q
Chimpanzee Pan troglodytes XP_001145351 1247 137800
Rhesus Macaque Macaca mulatta XP_001094709 1612 178491 S244 P F R S K I L S A K A E G E I
Dog Lupus familis XP_548204 1523 168842 G158 I L A A T A K G E V S D P F H
Cat Felis silvestris
Mouse Mus musculus O35379 1528 171166 S159 I L R S K I I S A L K K D A H
Rat Rattus norvegicus Q8CG09 1532 171475 S159 I L R S K I I S A L K K D A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517193 1537 172363 H171 I F R S K V L H S L K V D A E
Chicken Gallus gallus Q5F364 1525 170953 L159 I F R S K I M L A L N T D T E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341895 1518 169232 H159 T F R S K I M H A L N D P A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995704 1548 173512 L163 R C R T E V R L D A E R Q K I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42093 1623 182111 L158 L V G D M V L L N L V L S V K
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 G161 L I R H T Y E G I W Y S G Q T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.5 54.1 56.6 N.A. 88.1 87.4 N.A. 84.2 77.6 N.A. 70.5 N.A. 51.2 N.A. N.A. N.A.
Protein Similarity: 100 80.1 71 74.1 N.A. 94.7 93.8 N.A. 91.7 89.2 N.A. 83.2 N.A. 68.5 N.A. N.A. N.A.
P-Site Identity: 100 0 40 13.3 N.A. 73.3 80 N.A. 53.3 60 N.A. 53.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 0 53.3 33.3 N.A. 93.3 100 N.A. 80 66.6 N.A. 60 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.2 39.8 N.A.
Protein Similarity: N.A. N.A. N.A. 51.8 59.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 9 0 0 50 9 9 0 0 42 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 9 0 0 17 42 0 0 % D
% Glu: 0 0 0 0 9 0 9 0 9 0 9 17 0 9 17 % E
% Phe: 0 34 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 9 0 0 0 0 17 0 0 0 0 17 0 0 % G
% His: 0 0 0 9 0 0 0 17 0 0 0 0 0 0 17 % H
% Ile: 50 9 0 0 0 50 17 0 9 0 0 0 0 0 17 % I
% Lys: 0 0 0 0 59 0 9 0 0 9 34 17 0 9 9 % K
% Leu: 17 34 0 0 0 0 25 25 0 59 0 9 0 0 0 % L
% Met: 0 0 0 0 9 0 25 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 17 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 17 % Q
% Arg: 9 0 75 0 0 0 9 0 0 0 0 9 0 0 0 % R
% Ser: 0 0 0 59 0 0 0 25 9 0 9 9 9 0 9 % S
% Thr: 9 0 0 9 17 0 0 9 0 0 0 9 0 9 9 % T
% Val: 0 9 0 0 0 25 0 0 0 9 9 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _