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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC1
All Species:
4.55
Human Site:
T268
Identified Species:
9.09
UniProt:
P33527
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33527
NP_004987.2
1531
171561
T268
W
K
K
E
C
A
K
T
R
K
Q
P
V
K
V
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
F59
K
V
V
L
L
I
K
F
V
N
D
T
K
A
P
Rhesus Macaque
Macaca mulatta
XP_001094709
1612
178491
K351
E
A
W
R
K
Q
E
K
Q
T
A
R
H
K
A
Dog
Lupus familis
XP_548204
1523
168842
H265
L
Q
K
Q
A
V
G
H
E
A
A
A
A
S
G
Cat
Felis silvestris
Mouse
Mus musculus
O35379
1528
171166
R269
K
K
E
C
D
K
S
R
K
Q
P
V
R
I
V
Rat
Rattus norvegicus
Q8CG09
1532
171475
R269
K
K
E
C
V
K
S
R
K
Q
P
V
R
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
S280
W
A
K
E
C
T
K
S
K
K
Q
S
L
K
I
Chicken
Gallus gallus
Q5F364
1525
170953
K267
N
W
A
K
E
W
A
K
T
K
R
Q
P
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
K267
R
W
D
Q
E
C
V
K
V
K
R
P
V
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995704
1548
173512
W277
M
P
I
F
A
H
H
W
N
Q
N
V
R
K
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42093
1623
182111
T264
K
D
V
W
Y
L
D
T
W
D
Q
T
E
T
L
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
L267
E
K
N
W
E
N
E
L
K
Q
K
S
N
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
54.1
56.6
N.A.
88.1
87.4
N.A.
84.2
77.6
N.A.
70.5
N.A.
51.2
N.A.
N.A.
N.A.
Protein Similarity:
100
80.1
71
74.1
N.A.
94.7
93.8
N.A.
91.7
89.2
N.A.
83.2
N.A.
68.5
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
13.3
13.3
N.A.
53.3
6.6
N.A.
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
20
20
N.A.
33.3
33.3
N.A.
80
20
N.A.
33.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.2
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.8
59.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
17
9
9
0
0
9
17
9
9
9
9
% A
% Cys:
0
0
0
17
17
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
9
0
9
0
0
9
9
0
0
9
0
% D
% Glu:
17
0
17
17
25
0
17
0
9
0
0
0
9
0
0
% E
% Phe:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
9
9
9
0
0
0
0
9
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
0
0
0
17
9
% I
% Lys:
34
34
25
9
9
17
25
25
34
34
9
0
9
34
9
% K
% Leu:
9
0
0
9
9
9
0
9
0
0
0
0
9
9
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
9
0
0
9
9
9
0
9
0
17
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
17
17
9
9
9
% P
% Gln:
0
9
0
17
0
9
0
0
9
34
25
9
0
0
0
% Q
% Arg:
9
0
0
9
0
0
0
17
9
0
17
9
25
0
0
% R
% Ser:
0
0
0
0
0
0
17
9
0
0
0
17
0
9
9
% S
% Thr:
0
0
0
0
0
9
0
17
9
9
0
17
0
9
0
% T
% Val:
0
9
17
0
9
9
9
0
17
0
0
25
17
0
25
% V
% Trp:
17
17
9
17
0
9
0
9
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _