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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADORA3 All Species: 15.15
Human Site: Y222 Identified Species: 41.67
UniProt: P33765 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33765 NP_000668.1 318 36185 Y222 S K E T G A F Y G R E F K T A
Chimpanzee Pan troglodytes XP_001154129 326 36465 S219 N K K V S A S S G D P Q K Y Y
Rhesus Macaque Macaca mulatta Q28509 415 46453 L245 G R F H A Q N L S Q V E Q D G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q61618 319 36430 Y223 F R E T R A F Y G R E F K T A
Rat Rattus norvegicus P28647 320 36610 Y224 F R E T R A F Y G R E F K T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517742 348 39029 Y222 S K E A G T F Y G K E F K T A
Chicken Gallus gallus P49892 324 36305 S219 N K K V S S S S N D P Q K Y Y
Frog Xenopus laevis NP_001079313 326 36925 D217 K V C A N S K D P H K Y Y G K
Zebra Danio Brachydanio rerio NP_001122056 341 38506 N219 V S S H S E P N K Y Y D K E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.2 23.3 N.A. N.A. 72.7 74 N.A. 66 50.6 50 47.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 69 42.1 N.A. N.A. 84.3 86.2 N.A. 77 69.1 69.6 65.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 0 N.A. N.A. 80 80 N.A. 80 13.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 20 N.A. N.A. 86.6 86.6 N.A. 86.6 33.3 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 23 12 45 0 0 0 0 0 0 0 0 45 % A
% Cys: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 0 23 0 12 0 12 0 % D
% Glu: 0 0 45 0 0 12 0 0 0 0 45 12 0 12 0 % E
% Phe: 23 0 12 0 0 0 45 0 0 0 0 45 0 0 0 % F
% Gly: 12 0 0 0 23 0 0 0 56 0 0 0 0 12 12 % G
% His: 0 0 0 23 0 0 0 0 0 12 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 45 23 0 0 0 12 0 12 12 12 0 78 0 12 % K
% Leu: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 23 0 0 0 12 0 12 12 12 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 12 0 12 0 23 0 0 0 0 % P
% Gln: 0 0 0 0 0 12 0 0 0 12 0 23 12 0 0 % Q
% Arg: 0 34 0 0 23 0 0 0 0 34 0 0 0 0 0 % R
% Ser: 23 12 12 0 34 23 23 23 12 0 0 0 0 0 0 % S
% Thr: 0 0 0 34 0 12 0 0 0 0 0 0 0 45 0 % T
% Val: 12 12 0 23 0 0 0 0 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 45 0 12 12 12 12 23 23 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _