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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAN1A1
All Species:
16.97
Human Site:
S224
Identified Species:
41.48
UniProt:
P33908
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33908
NP_005898.2
653
72969
S224
L
N
E
L
K
P
I
S
K
G
G
H
S
S
S
Chimpanzee
Pan troglodytes
XP_518868
1022
112702
S593
L
N
E
L
K
P
I
S
K
G
G
H
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001113216
658
75038
R210
N
E
L
R
P
I
A
R
K
G
H
S
P
N
I
Dog
Lupus familis
XP_533481
627
70707
S198
L
N
E
L
K
P
I
S
K
E
G
H
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P45700
655
73257
S226
L
N
E
L
K
P
I
S
K
E
G
H
S
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510614
483
55360
W94
E
F
K
E
A
K
E
W
V
E
K
N
L
E
F
Chicken
Gallus gallus
XP_419762
518
58089
E127
E
E
F
K
E
A
K
E
W
V
E
K
N
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694435
618
69847
S189
S
N
E
L
R
P
V
S
K
Q
G
H
S
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P53624
667
74947
R231
E
L
R
P
L
S
Q
R
P
H
S
A
S
I
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18788
590
66931
K169
N
E
L
R
P
M
S
K
K
P
N
S
Q
N
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.5
60.4
80.4
N.A.
90.6
N.A.
N.A.
63.8
67.2
N.A.
69.8
N.A.
45.1
N.A.
40.7
N.A.
Protein Similarity:
100
63.7
75
85.3
N.A.
94.6
N.A.
N.A.
69.2
72.5
N.A.
80.5
N.A.
60.5
N.A.
57.5
N.A.
P-Site Identity:
100
100
13.3
93.3
N.A.
93.3
N.A.
N.A.
0
0
N.A.
66.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
N.A.
N.A.
13.3
13.3
N.A.
86.6
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
10
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
30
30
50
10
10
0
10
10
0
30
10
0
0
10
0
% E
% Phe:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
20
% F
% Gly:
0
0
0
0
0
0
0
0
0
30
50
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
10
50
0
0
0
% H
% Ile:
0
0
0
0
0
10
40
0
0
0
0
0
0
10
20
% I
% Lys:
0
0
10
10
40
10
10
10
70
0
10
10
0
0
0
% K
% Leu:
40
10
20
50
10
0
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
50
0
0
0
0
0
0
0
0
10
10
10
20
10
% N
% Pro:
0
0
0
10
20
50
0
0
10
10
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
10
0
0
10
0
0
% Q
% Arg:
0
0
10
20
10
0
0
20
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
10
10
50
0
0
10
20
60
50
40
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _