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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAN1A1 All Species: 30.91
Human Site: S426 Identified Species: 75.56
UniProt: P33908 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33908 NP_005898.2 653 72969 S426 L L K A W L M S D K T D L E A
Chimpanzee Pan troglodytes XP_518868 1022 112702 S795 L L K A W L M S D K T D L E A
Rhesus Macaque Macaca mulatta XP_001113216 658 75038 S412 L L K A W L M S D K T D H E A
Dog Lupus familis XP_533481 627 70707 S400 L L K A W L M S D K T D L E A
Cat Felis silvestris
Mouse Mus musculus P45700 655 73257 S428 L L K A W L M S D K T D L E A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510614 483 55360 Y289 K S S S G L T Y I A E W K G G
Chicken Gallus gallus XP_419762 518 58089 T322 R K S S G G L T Y I A E W K G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694435 618 69847 S391 L L K A W L M S D K I D E E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P53624 667 74947 S433 L L K A W L Q S G Q T D E E A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18788 590 66931 S372 L I K S Y V Q S N Y T D T Q A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.5 60.4 80.4 N.A. 90.6 N.A. N.A. 63.8 67.2 N.A. 69.8 N.A. 45.1 N.A. 40.7 N.A.
Protein Similarity: 100 63.7 75 85.3 N.A. 94.6 N.A. N.A. 69.2 72.5 N.A. 80.5 N.A. 60.5 N.A. 57.5 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 100 N.A. N.A. 6.6 0 N.A. 80 N.A. 73.3 N.A. 40 N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 100 N.A. N.A. 13.3 33.3 N.A. 80 N.A. 80 N.A. 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 70 0 0 0 0 0 10 10 0 0 0 70 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 60 0 0 80 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 10 20 70 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 20 10 0 0 10 0 0 0 0 10 30 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 10 10 10 0 0 0 0 % I
% Lys: 10 10 80 0 0 0 0 0 0 60 0 0 10 10 0 % K
% Leu: 80 70 0 0 0 80 10 0 0 0 0 0 40 0 0 % L
% Met: 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 20 0 0 10 0 0 0 10 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 20 30 0 0 0 80 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 10 0 0 70 0 10 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 70 0 0 0 0 0 0 10 10 0 0 % W
% Tyr: 0 0 0 0 10 0 0 10 10 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _