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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDELR2 All Species: 39.7
Human Site: S28 Identified Species: 67.18
UniProt: P33947 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33947 NP_001094073.1 212 24422 S28 L K I W K T R S C A G I S G K
Chimpanzee Pan troglodytes XP_001163595 214 24981 C28 G K I W R S K C C T G I S G K
Rhesus Macaque Macaca mulatta XP_001093907 223 25854 C28 G K I W R S K C C T G I S G K
Dog Lupus familis XP_861472 217 24988 S33 T R S C A G I S G K S Q L L F
Cat Felis silvestris
Mouse Mus musculus Q99JH8 212 24542 S28 L K I W K S R S C A G I S G K
Rat Rattus norvegicus Q5U305 212 24435 S28 L K I W K T R S C A G I S G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKX9 212 24437 S28 L K I W K S R S C A G I S G K
Frog Xenopus laevis Q7ZXS5 212 24325 S28 L K I W N S R S C A G I S G K
Zebra Danio Brachydanio rerio Q6PEH1 212 24305 S28 L K I W K S R S C A G I S G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76767 212 24463 S28 L K I W K T R S C A G I S G K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P48583 213 25042 S28 L K I W K S R S C E G I S G R
Sea Urchin Strong. purpuratus XP_001178364 212 24343 S28 K K I W S S R S C A G I S G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P35402 215 25185 S28 L K I Y A T K S C A G I S L K
Baker's Yeast Sacchar. cerevisiae P18414 219 25744 F34 R Y I E G I S F K T Q T L Y A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.6 73 96.3 N.A. 83 98.5 N.A. N.A. 95.7 92.4 91.5 N.A. 74 N.A. 65.2 84.9
Protein Similarity: 100 87.8 84.7 97.6 N.A. 93.8 100 N.A. N.A. 100 97.1 96.6 N.A. 90 N.A. 84 94.3
P-Site Identity: 100 60 60 6.6 N.A. 93.3 100 N.A. N.A. 93.3 86.6 93.3 N.A. 100 N.A. 80 80
P-Site Similarity: 100 80 80 13.3 N.A. 100 100 N.A. N.A. 100 93.3 100 N.A. 100 N.A. 93.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 50.2 49.3 N.A.
Protein Similarity: N.A. N.A. N.A. 69.7 68 N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 0 0 0 65 0 0 0 0 8 % A
% Cys: 0 0 0 8 0 0 0 15 86 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % F
% Gly: 15 0 0 0 8 8 0 0 8 0 86 0 0 79 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 93 0 0 8 8 0 0 0 0 86 0 0 0 % I
% Lys: 8 86 0 0 50 0 22 0 8 8 0 0 0 0 79 % K
% Leu: 65 0 0 0 0 0 0 0 0 0 0 0 15 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 8 8 0 0 15 0 65 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 8 0 8 58 8 79 0 0 8 0 86 0 0 % S
% Thr: 8 0 0 0 0 29 0 0 0 22 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 79 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _