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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDELR2 All Species: 40.61
Human Site: Y76 Identified Species: 68.72
UniProt: P33947 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33947 NP_001094073.1 212 24422 Y76 A C S Y A T V Y L I Y L K F K
Chimpanzee Pan troglodytes XP_001163595 214 24981 Y76 L C A Y V T V Y M I Y G K F R
Rhesus Macaque Macaca mulatta XP_001093907 223 25854 Y76 L C A Y V T V Y M I Y G K F R
Dog Lupus familis XP_861472 217 24988 Y81 A C S Y A T V Y L I Y M K F K
Cat Felis silvestris
Mouse Mus musculus Q99JH8 212 24542 W76 A C S F T T V W M I Y S K F K
Rat Rattus norvegicus Q5U305 212 24435 Y76 A C S Y A T V Y L I Y M K F K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKX9 212 24437 Y76 A C S Y A T V Y L I Y M K F K
Frog Xenopus laevis Q7ZXS5 212 24325 Y76 G C A Y A T V Y L I Y M K F K
Zebra Danio Brachydanio rerio Q6PEH1 212 24305 Y76 G C A Y A T V Y L I Y A K F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76767 212 24463 Y76 A T S G A T V Y L M Y V K F K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P48583 213 25042 Y76 V A S F G T V Y L M W A K F K
Sea Urchin Strong. purpuratus XP_001178364 212 24343 Y76 L C A Y A T V Y L I Y V K F K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P35402 215 25185 W76 A S S L A I V W C M R R H P L
Baker's Yeast Sacchar. cerevisiae P18414 219 25744 S82 I V V L L Q G S K R T N T I A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.6 73 96.3 N.A. 83 98.5 N.A. N.A. 95.7 92.4 91.5 N.A. 74 N.A. 65.2 84.9
Protein Similarity: 100 87.8 84.7 97.6 N.A. 93.8 100 N.A. N.A. 100 97.1 96.6 N.A. 90 N.A. 84 94.3
P-Site Identity: 100 60 60 93.3 N.A. 66.6 93.3 N.A. N.A. 93.3 80 73.3 N.A. 73.3 N.A. 53.3 80
P-Site Similarity: 100 80 80 100 N.A. 86.6 100 N.A. N.A. 100 93.3 86.6 N.A. 86.6 N.A. 73.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 50.2 49.3 N.A.
Protein Similarity: N.A. N.A. N.A. 69.7 68 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 8 36 0 65 0 0 0 0 0 0 15 0 0 8 % A
% Cys: 0 72 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 15 0 0 0 0 0 0 0 0 0 86 0 % F
% Gly: 15 0 0 8 8 0 8 0 0 0 0 15 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 0 0 8 0 0 0 72 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 86 0 65 % K
% Leu: 22 0 0 15 8 0 0 0 65 0 0 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 22 22 0 29 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 22 % R
% Ser: 0 8 58 0 0 0 0 8 0 0 0 8 0 0 0 % S
% Thr: 0 8 0 0 8 86 0 0 0 0 8 0 8 0 0 % T
% Val: 8 8 8 0 15 0 93 0 0 0 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 15 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 65 0 0 0 79 0 0 79 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _