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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
8.48
Human Site:
S196
Identified Species:
15.56
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
S196
L
Q
K
K
Q
L
L
S
E
E
E
K
K
N
L
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
S196
L
Q
K
K
Q
L
L
S
E
E
E
K
K
N
L
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
G157
A
Q
F
E
L
S
Q
G
N
V
K
K
S
K
Q
Dog
Lupus familis
XP_539016
855
96614
L194
L
N
L
Q
K
K
Q
L
L
S
E
E
E
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
P192
L
Q
K
K
Q
L
L
P
E
E
D
K
K
S
V
Rat
Rattus norvegicus
NP_001101642
835
94323
Q174
E
T
G
A
V
P
L
Q
M
L
E
T
A
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
E199
R
Q
L
L
S
E
E
E
K
E
N
F
S
V
S
Chicken
Gallus gallus
XP_419867
879
99691
S200
S
Q
K
K
Q
L
L
S
D
E
E
K
E
N
F
Frog
Xenopus laevis
NP_001082090
882
99060
D198
K
K
P
Q
L
I
S
D
E
D
K
E
N
L
A
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
D258
I
P
E
N
E
T
S
D
S
D
C
A
Q
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
G171
V
E
S
Q
L
F
E
G
K
R
K
V
Q
F
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
V156
S
L
E
S
N
L
D
V
Q
R
K
S
Q
S
L
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
D143
L
R
Q
N
M
K
E
D
I
T
A
K
Y
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
73.3
13.3
N.A.
13.3
73.3
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
40
N.A.
93.3
13.3
N.A.
20
86.6
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
0
8
8
8
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
24
8
16
8
0
0
0
0
% D
% Glu:
8
8
16
8
8
8
24
8
31
39
39
16
16
0
8
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
8
0
8
8
% F
% Gly:
0
0
8
0
0
0
0
16
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% I
% Lys:
8
8
31
31
8
16
0
0
16
0
31
47
24
24
8
% K
% Leu:
39
8
16
8
24
39
39
8
8
8
0
0
0
8
31
% L
% Met:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
16
8
0
0
0
8
0
8
0
8
24
0
% N
% Pro:
0
8
8
0
0
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
47
8
24
31
0
16
8
8
0
0
0
24
0
8
% Q
% Arg:
8
8
0
0
0
0
0
0
0
16
0
0
0
0
8
% R
% Ser:
16
0
8
8
8
8
16
24
8
8
0
8
16
16
8
% S
% Thr:
0
8
0
0
0
8
0
0
0
8
0
8
0
0
0
% T
% Val:
8
0
0
0
8
0
0
8
0
8
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _