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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
18.48
Human Site:
S206
Identified Species:
33.89
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
S206
E
K
K
N
L
S
A
S
T
V
L
T
A
Q
E
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
S206
E
K
K
N
L
S
A
S
T
V
L
T
A
Q
E
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
Q167
K
K
S
K
Q
L
L
Q
K
A
V
E
R
G
A
Dog
Lupus familis
XP_539016
855
96614
S204
E
E
E
K
K
S
L
S
V
S
M
V
L
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
S202
D
K
K
S
V
S
A
S
T
V
L
S
A
Q
E
Rat
Rattus norvegicus
NP_001101642
835
94323
H184
E
T
A
I
R
N
L
H
L
Q
K
K
Q
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
M209
N
F
S
V
S
S
T
M
P
S
Q
D
S
F
P
Chicken
Gallus gallus
XP_419867
879
99691
S210
E
K
E
N
F
A
A
S
Y
L
K
I
G
K
K
Frog
Xenopus laevis
NP_001082090
882
99060
S208
K
E
N
L
A
V
S
S
S
H
I
N
Q
G
T
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
P268
C
A
Q
K
A
E
A
P
F
T
H
S
S
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
N181
K
V
Q
F
L
T
V
N
K
A
T
S
Q
E
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
T166
K
S
Q
S
L
I
G
T
S
Q
D
M
E
W
D
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
S153
A
K
Y
A
E
R
R
S
K
R
F
L
I
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
20
N.A.
73.3
6.6
N.A.
6.6
33.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
40
N.A.
100
13.3
N.A.
13.3
66.6
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
16
8
39
0
0
16
0
0
24
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% D
% Glu:
39
16
16
0
8
8
0
0
0
0
0
8
8
8
24
% E
% Phe:
0
8
0
8
8
0
0
0
8
0
8
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
8
24
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
8
8
8
0
0
% I
% Lys:
31
47
24
24
8
0
0
0
24
0
16
8
0
8
8
% K
% Leu:
0
0
0
8
31
8
24
0
8
8
24
8
8
8
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
8
% M
% Asn:
8
0
8
24
0
8
0
8
0
0
0
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% P
% Gln:
0
0
24
0
8
0
0
8
0
16
8
0
24
24
0
% Q
% Arg:
0
0
0
0
8
8
8
0
0
8
0
0
8
0
0
% R
% Ser:
0
8
16
16
8
39
8
54
16
16
0
24
16
8
0
% S
% Thr:
0
8
0
0
0
8
8
8
24
8
8
16
0
8
16
% T
% Val:
0
8
0
8
8
8
8
0
8
24
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _