KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
20.3
Human Site:
S511
Identified Species:
37.22
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
S511
Q
N
L
Q
V
L
A
S
S
S
A
N
E
C
I
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
S511
Q
N
L
Q
V
L
A
S
S
S
A
N
E
C
I
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
V471
S
C
F
R
T
P
V
V
K
N
D
F
P
P
A
Dog
Lupus familis
XP_539016
855
96614
A508
L
Q
T
L
Q
I
S
A
S
S
T
N
E
C
I
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
S510
Q
S
L
Q
I
S
G
S
S
S
I
N
E
C
I
Rat
Rattus norvegicus
NP_001101642
835
94323
S489
Q
N
L
Q
I
S
G
S
S
S
M
S
E
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
S522
Q
S
F
Q
V
P
P
S
F
S
S
N
E
C
I
Chicken
Gallus gallus
XP_419867
879
99691
S528
M
G
L
Q
V
S
G
S
I
P
S
N
E
C
I
Frog
Xenopus laevis
NP_001082090
882
99060
P532
D
C
F
P
I
S
A
P
F
A
S
S
D
C
I
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
S639
P
P
T
Q
T
P
S
S
A
F
S
N
E
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
K498
Y
L
N
K
L
K
G
K
N
N
I
I
Q
L
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
K470
I
D
Y
E
V
T
D
K
T
L
L
Q
E
V
L
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
V457
G
S
S
R
V
Y
K
V
K
G
S
G
N
R
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
40
N.A.
66.6
66.6
N.A.
60
53.3
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
60
N.A.
80
80
N.A.
73.3
60
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
24
8
8
8
16
0
0
0
8
% A
% Cys:
0
16
0
0
0
0
0
0
0
0
0
0
0
62
0
% C
% Asp:
8
8
0
0
0
0
8
0
0
0
8
0
8
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
70
0
0
% E
% Phe:
0
0
24
0
0
0
0
0
16
8
0
8
0
0
0
% F
% Gly:
8
8
0
0
0
0
31
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
24
8
0
0
8
0
16
8
0
0
77
% I
% Lys:
0
0
0
8
0
8
8
16
16
0
0
0
0
0
0
% K
% Leu:
8
8
39
8
8
16
0
0
0
8
8
0
0
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
24
8
0
0
0
0
0
8
16
0
54
8
0
0
% N
% Pro:
8
8
0
8
0
24
8
8
0
8
0
0
8
8
0
% P
% Gln:
39
8
0
54
8
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
24
8
0
0
31
16
54
39
47
39
16
0
8
0
% S
% Thr:
0
0
16
0
16
8
0
0
8
0
8
0
0
0
0
% T
% Val:
0
0
0
0
47
0
8
16
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _