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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
13.03
Human Site:
T795
Identified Species:
23.89
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
T795
H
P
Y
V
Q
I
Q
T
H
P
V
N
Q
M
A
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
T795
H
P
Y
V
Q
I
Q
T
H
P
G
N
Q
M
A
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
K717
C
C
L
K
R
D
P
K
Q
R
I
S
I
P
E
Dog
Lupus familis
XP_539016
855
96614
T792
H
P
Y
V
Q
I
Q
T
H
P
G
N
Q
M
A
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
P794
H
P
Y
V
Q
I
Q
P
H
P
G
S
Q
M
A
Rat
Rattus norvegicus
NP_001101642
835
94323
P773
H
P
Y
V
Q
I
Q
P
H
P
G
S
Q
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
T806
H
P
Y
V
H
I
Q
T
Q
A
Q
P
G
K
A
Chicken
Gallus gallus
XP_419867
879
99691
C815
Y
V
Q
I
Q
T
Q
C
Q
T
G
V
A
N
A
Frog
Xenopus laevis
NP_001082090
882
99060
T818
Y
V
Q
I
Q
P
H
T
Q
P
D
Q
Q
V
Q
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
P920
H
P
Y
L
Q
L
Q
P
Q
P
A
P
E
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
L753
S
Q
K
Q
G
C
K
L
L
Q
L
V
S
E
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
C716
F
S
L
I
A
E
S
C
G
S
D
D
D
K
A
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
K703
C
L
Y
R
N
P
D
K
R
W
T
V
D
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
0
93.3
N.A.
80
80
N.A.
53.3
20
26.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
20
93.3
N.A.
86.6
86.6
N.A.
53.3
33.3
46.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
8
8
0
8
0
70
% A
% Cys:
16
8
0
0
0
8
0
16
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
0
0
0
16
8
16
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
8
0
39
0
8
0
0
% G
% His:
54
0
0
0
8
0
8
0
39
0
0
0
0
0
0
% H
% Ile:
0
0
0
24
0
47
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
0
8
8
0
0
8
16
0
0
0
0
0
24
0
% K
% Leu:
0
8
16
8
0
8
0
8
8
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
24
0
8
0
% N
% Pro:
0
54
0
0
0
16
8
24
0
54
0
16
0
16
0
% P
% Gln:
0
8
16
8
62
0
62
0
39
8
8
8
47
0
8
% Q
% Arg:
0
0
0
8
8
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
8
8
0
0
0
0
8
0
0
8
0
24
8
0
0
% S
% Thr:
0
0
0
0
0
8
0
39
0
8
8
0
0
0
8
% T
% Val:
0
16
0
47
0
0
0
0
0
0
8
24
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
16
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _