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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
13.33
Human Site:
T849
Identified Species:
24.44
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
T849
H
N
S
S
S
S
K
T
F
E
K
K
R
G
K
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
T849
H
N
S
S
S
S
K
T
F
E
K
K
R
G
K
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
N771
S
I
L
K
A
A
K
N
I
M
L
D
S
V
L
Dog
Lupus familis
XP_539016
855
96614
K846
H
D
S
S
S
S
S
K
T
F
E
N
K
W
E
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
T848
Q
D
S
S
S
S
K
T
F
D
K
K
R
E
R
Rat
Rattus norvegicus
NP_001101642
835
94323
T827
Q
A
P
S
S
S
K
T
S
D
K
K
R
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
R860
R
D
V
S
S
P
A
R
R
S
D
R
K
R
G
Chicken
Gallus gallus
XP_419867
879
99691
K869
L
D
V
S
A
F
A
K
S
G
S
Q
K
S
W
Frog
Xenopus laevis
NP_001082090
882
99060
T872
L
D
L
S
T
L
G
T
T
V
S
Q
N
T
R
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
K974
L
D
V
S
E
C
V
K
S
S
S
Q
T
L
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
Q807
Q
M
S
K
L
C
F
Q
L
R
E
C
L
A
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
L770
C
I
Q
L
Q
D
R
L
Q
G
L
E
G
E
N
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
R757
D
V
V
D
T
V
L
R
K
F
A
D
Y
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
33.3
N.A.
66.6
53.3
N.A.
13.3
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
60
N.A.
86.6
66.6
N.A.
33.3
33.3
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
16
8
16
0
0
0
8
0
0
8
0
% A
% Cys:
8
0
0
0
0
16
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
47
0
8
0
8
0
0
0
16
8
16
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
16
16
8
0
24
8
% E
% Phe:
0
0
0
0
0
8
8
0
24
16
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
16
0
0
8
16
8
% G
% His:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
16
0
0
39
24
8
0
31
31
24
8
24
% K
% Leu:
24
0
16
8
8
8
8
8
8
0
16
0
8
8
8
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
16
0
0
0
0
0
8
0
0
0
8
8
0
8
% N
% Pro:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
24
0
8
0
8
0
0
8
8
0
0
24
0
0
0
% Q
% Arg:
8
0
0
0
0
0
8
16
8
8
0
8
31
8
24
% R
% Ser:
8
0
39
70
47
39
8
0
24
16
24
0
8
8
0
% S
% Thr:
0
0
0
0
16
0
0
39
16
0
0
0
8
8
0
% T
% Val:
0
8
31
0
0
8
8
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
16
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _